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NCT01606761 · ClinicalTrials.gov registry record · Phase 3

A Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy (SIRROUND-T)

A Phase 3 study, sponsored by Janssen Research & Development.

Completed
Registry status
Phase 3
Development phase
878
Enrollment target

NCT01606761 is a Phase 3 study that has completed, run by Janssen Research & Development. The registered enrollment target is 878 participants.

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The verdict

NCT01606761, a Phase 3 study, has completed, sponsored by Janssen Research & Development.

COMPLETED
Registry status
Phase 3
Development phase
878 participants
Enrollment target

Study Summary

The purpose of this study is to assess the efficacy of sirukumab as measured by the reduction of the signs and symptoms of rheumatoid arthritis (RA) in patients with active RA who are unresponsive or intolerant to treatment with anti-TNF-alpha agents.

Interventions

  • DRUG Placebo
  • DRUG Sirukumab

Trial Details

FieldValue
Enrollment Target 878 participants
Start Date 2012-08-06
Est. Completion 2016-01-12
Phase Phase 3

Sponsor

Janssen Research & Development

593 total trials

What the Registry Record Tells You About NCT01606761

The ClinicalTrials.gov registry entry for NCT01606761 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 878 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01606761 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01606761 about?

NCT01606761 is a clinical study titled "A Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy (SIRROUND-T)". The purpose of this study is to assess the efficacy of sirukumab as measured by the reduction of the signs and symptoms of rheumatoid arthritis (RA) in patients with active RA who are unresponsive or intolerant to treatment with anti-TNF-alpha agents.

What is the current status of trial NCT01606761?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 878 participants. The study started on 2012-08-06. Estimated completion is 2016-01-12.

What interventions are being tested in trial NCT01606761?

The interventions under investigation include: Placebo (DRUG), Sirukumab (DRUG).

Who is sponsoring clinical trial NCT01606761?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.