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NCT01600885 · ClinicalTrials.gov registry record · NA

The Effects of Ketamine and Guanfacine on Working Memory in Healthy Subjects

A NA study, sponsored by Yale University.

Completed
Registry status
NA
Development phase
16
Enrollment target

NCT01600885: Completed NA study, sponsored by Yale University.

NCT01600885 is a NA study that has completed, run by Yale University. The registered enrollment target is 16 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01600885, a NA study, has completed, sponsored by Yale University.

COMPLETED
Registry status
NA
Development phase
16 participants
Enrollment target

Study Summary

The purpose of the study is 1. To establish the feasibility of fMRI studies of the interaction of guanfacine and ketamine. 2. To explore the possibility that guanfacine can ameliorate the negative effects of ketamine on task-related prefrontal activation. 3. To assess the strength of any interaction between guanfacine and ketamine.

Primary Outcome

Scans will be analyzed for task-related prefrontal activation Difference Score: Percent Signal Change in Regions of Interest (ketamine - saline)

Interventions

  • DRUG Placebo
  • DRUG Guanfacine

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2008-08
Est. Completion 2014-12
Phase NA
Yale University

1,492 total trials

What the finished NCT01600885 record still lists

NCT01600885 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01600885 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01600885 about?

NCT01600885 is a clinical study titled "The Effects of Ketamine and Guanfacine on Working Memory in Healthy Subjects". The purpose of the study is 1. To establish the feasibility of fMRI studies of the interaction of guanfacine and ketamine. 2. To explore the possibility that guanfacine can ameliorate the negative effects of ketamine on task-related prefrontal activation. 3. To assess the strength of any interactio...

What is the current status of trial NCT01600885?

This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2008-08. Estimated completion is 2014-12.

What interventions are being tested in trial NCT01600885?

The interventions under investigation include: Placebo (DRUG), Guanfacine (DRUG).

Who is sponsoring clinical trial NCT01600885?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01600885's enrollment target sits among peer trials

16 1871st of 2000 higher than 120 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01600885, the US trial registry maintained by the National Library of Medicine. NCT01600885 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.