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NCT01586871 · ClinicalTrials.gov registry record
Carotid Structure and Function in MPS Syndromes: A Multicenter Study of the Lysosomal Disease Network
A clinical trial, sponsored by University of Minnesota.
- Completed
- Registry status
- 1,147
- Enrollment target
NCT01586871: Completed study, sponsored by University of Minnesota.
NCT01586871 is a clinical trial that has completed, run by University of Minnesota. The registered enrollment target is 1,147 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01586871 has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- 1,147 participants
- Enrollment target
Study Summary
Mucopolysaccharidosis (MPS) syndromes are disorders characterized by enzyme deficiencies, and they have been linked to heart health complications. However, there are currently no proven markers of heart and artery health for this population. The main purpose of this observational study is to evaluate the ease and convenience of a non-invasive measurement of artery function in MPS I, MPS II and MPS VI patients compared to healthy control subjects. An observational study is a research design meaning that there is no treatment in this study. The research questions are: 1. Is the artery health of MPS I, II and VI patients different than healthy controls? 2. Is the artery health of MPS VI patients different than MPS I and II patients? It is hypothesized that MPS patients will have poorer outcomes of artery health compared to healthy controls.
Primary Outcome
The carotid intima-media thickness test (CIMT) is a measure used to diagnose the extent of carotid atherosclerotic vascular disease. The test measures the thickness of the inner two layers of the carotid artery-the intima and media-and alerts physicians to any thickening when patients are still asymptomatic. CIMT was measured from the far wall of the left common carotid.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,147 participants |
| Start Date | 2012-03 |
| Est. Completion | 2017-06 |
What the finished NCT01586871 record still lists
NCT01586871 is an observational study that tracks outcomes without assigning an intervention. Its 1,147 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT01586871 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01586871 about?
NCT01586871 is a clinical study titled "Carotid Structure and Function in MPS Syndromes: A Multicenter Study of the Lysosomal Disease Network". Mucopolysaccharidosis (MPS) syndromes are disorders characterized by enzyme deficiencies, and they have been linked to heart health complications. However, there are currently no proven markers of heart and artery health for this population. The main purpose of this observational study is to evaluat...
What is the current status of trial NCT01586871?
This trial is currently completed. The enrollment target is 1,147 participants. The study started on 2012-03. Estimated completion is 2017-06.
Who is sponsoring clinical trial NCT01586871?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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