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NCT01578486 · ClinicalTrials.gov registry record · Phase 4
Salsalate as an Adjunctive Treatment for Patients With Schizophrenia
A Phase 4 study, sponsored by University of Massachusetts, Worcester.
- Completed
- Registry status
- Phase 4
- Development phase
- 17
- Enrollment target
NCT01578486: Completed Phase 4 study, sponsored by University of Massachusetts, Worcester.
NCT01578486 is a Phase 4 study that has completed, run by University of Massachusetts, Worcester. The registered enrollment target is 17 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01578486, a Phase 4 study, has completed, sponsored by University of Massachusetts, Worcester.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 17 participants
- Enrollment target
Study Summary
This is a 12-week, open-label trial of salsalate 3 g/day as an adjunctive treatment in 15 schizophrenia subjects to examine salsalate's effect on psychopathology, cognitive functioning, and metabolic parameters. Potential subjects will be identified by their clinicians at the Freedom Trail Clinic, or Massachusetts General Hospital. A total of 15 subjects will be enrolled.
Primary Outcome
Positive and negative symptoms of schizophrenia will be measured by total score on all subscales of the Positive and Negative Syndrome Scale (PANSS; score range 30-210). Higher scores correspond with worse outcomes.
Interventions
- DRUG salsalate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2011-06 |
| Est. Completion | 2015-07 |
| Phase | Phase 4 |
What the finished NCT01578486 record still lists
NCT01578486 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which salsalate is the first listed.
NCT01578486 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01578486 about?
NCT01578486 is a clinical study titled "Salsalate as an Adjunctive Treatment for Patients With Schizophrenia". This is a 12-week, open-label trial of salsalate 3 g/day as an adjunctive treatment in 15 schizophrenia subjects to examine salsalate's effect on psychopathology, cognitive functioning, and metabolic parameters. Potential subjects will be identified by their clinicians at the Freedom Trail Clinic, ...
What is the current status of trial NCT01578486?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 17 participants. The study started on 2011-06. Estimated completion is 2015-07.
What interventions are being tested in trial NCT01578486?
The interventions under investigation include: salsalate (DRUG).
Who is sponsoring clinical trial NCT01578486?
This trial is sponsored by University of Massachusetts, Worcester, which has 240 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01578486's enrollment target sits among peer trials
17 1854th of 2000 higher than 132 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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