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NCT01576406 · ClinicalTrials.gov registry record · Phase 1
Hepatic Impairment Study For Crizotinib In Advanced Cancer Patients
A Phase 1 study of Advanced Cancer, sponsored by Pfizer.
- Completed
- Registry status
- Phase 1
- Development phase
- 88
- Enrollment target
- 20
- Study locations
NCT01576406 is a Phase 1 study of Advanced Cancer that has completed, run by Pfizer. The registered enrollment target is 88 participants, below the 246-participant average among 122 other Advanced Cancer trials with a reported enrollment target (64% lower). The trial reports 20 study locations across 5 states.
The verdict
NCT01576406, a Phase 1 study of Advanced Cancer, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 88 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study is designed to evaluate the potential effect of hepatic impairment on the pharmacokinetics and safety of crizotinib in advanced cancer patients. Advanced cancer patients with mild, moderate or severe liver dysfunction as well as patients with normal liver function will be enrolled in this study.
Conditions Studied
Interventions
- DRUG crizotinib
Study Locations (20)
Georgia
- Emory University Hospital Midtown Laboratory - Atlanta
- Emory University Hospital - Atlanta
- Investigational Drug Service: The Emory Clinic Bldg A - Atlanta
- The Emory Clinic - Atlanta
- Winship Cancer Institute - Atlanta
Ohio
- University Hospital East - Columbus
- Investigational Drug Services - Columbus
- James Cancer Hospital - Columbus
- The Ohio State University, Wexner Medical Center - Columbus
- Martha Morehouse Medical Plaza - Columbus
California
- Keck Hospital of USC - Los Angeles
- LAC&USC Medical Center - Los Angeles
- USC/Norris Comprehensive Cancer Center / Investigational Drug Services - Los Angeles
- USC/Norris Comprehensive Cancer Center - Los Angeles
Colorado
- Anschutz Cancer Pavilion, Room 2224, c/o Melinda Friesleben, Pharm D - Aurora
- University of Colorado Denver - Clinical Translational Research Center - Aurora
- University of Colorado Denver, Anschutz Cancer Pavilion - Aurora
- University of Colorado Denver, Anschutz Inpatient Pavillion - Aurora
Texas
- Cancer Therapy & Research Center at UTHSCSA - San Antonio
- Medical Arts and Research Center-MARC - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2012-07 |
| Est. Completion | 2016-06 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01576406
The ClinicalTrials.gov registry entry for NCT01576406 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 246-participant average among 122 other Advanced Cancer trials with a reported enrollment target (64% lower). The listed sponsor is Pfizer, which has 1,845 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Advanced Cancer appearing as the primary indexed condition, and to 1 intervention - of which crizotinib is the first listed.
NCT01576406 reports 20 study locations spanning 5 distinct geographic areas - top geographies include Georgia, Ohio, California.
Frequently Asked Questions
What is clinical trial NCT01576406 about?
NCT01576406 is a clinical study titled "Hepatic Impairment Study For Crizotinib In Advanced Cancer Patients". This study is designed to evaluate the potential effect of hepatic impairment on the pharmacokinetics and safety of crizotinib in advanced cancer patients. Advanced cancer patients with mild, moderate or severe liver dysfunction as well as patients with normal liver function will be enrolled in this...
What is the current status of trial NCT01576406?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 88 participants. The study started on 2012-07. Estimated completion is 2016-06.
What conditions does trial NCT01576406 study?
This clinical trial studies the following conditions: Advanced Cancer.
What interventions are being tested in trial NCT01576406?
The interventions under investigation include: crizotinib (DRUG).
Who is sponsoring clinical trial NCT01576406?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01576406 being conducted?
This trial has 20 study locations across California, Colorado, Georgia, Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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