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NCT01569750 · ClinicalTrials.gov registry record · Phase 1

A Study Combining Ibrutinib With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With CD20-Positive B-Cell Non Hodgkin Lymphoma

A Phase 1 study, sponsored by Janssen Research & Development.

Completed
Registry status
Phase 1
Development phase
33
Enrollment target

NCT01569750 is a Phase 1 study that has completed, run by Janssen Research & Development. The registered enrollment target is 33 participants.

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The verdict

NCT01569750, a Phase 1 study, has completed, sponsored by Janssen Research & Development.

COMPLETED
Registry status
Phase 1
Development phase
33 participants
Enrollment target

Study Summary

The purpose of this study is to identify if, and at what dose, ibrutinib may be administered with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) and to document responses of this combination in patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL).

Interventions

  • DRUG Part 1, Cohort 1
  • DRUG Part 1, Cohort 2
  • DRUG Part 1, Cohort 3
  • DRUG Part 2, Cohort 1
  • DRUG Part 2, Cohort 2

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2012-06-14
Est. Completion 2014-09-04
Phase Phase 1

Sponsor

Janssen Research & Development

593 total trials

What the Registry Record Tells You About NCT01569750

The ClinicalTrials.gov registry entry for NCT01569750 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Part 1, Cohort 1 is the first listed.

NCT01569750 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01569750 about?

NCT01569750 is a clinical study titled "A Study Combining Ibrutinib With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With CD20-Positive B-Cell Non Hodgkin Lymphoma". The purpose of this study is to identify if, and at what dose, ibrutinib may be administered with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) and to document responses of this combination in patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL).

What is the current status of trial NCT01569750?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 33 participants. The study started on 2012-06-14. Estimated completion is 2014-09-04.

What interventions are being tested in trial NCT01569750?

The interventions under investigation include: Part 1, Cohort 1 (DRUG), Part 1, Cohort 2 (DRUG), Part 1, Cohort 3 (DRUG), Part 2, Cohort 1 (DRUG), Part 2, Cohort 2 (DRUG).

Who is sponsoring clinical trial NCT01569750?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.