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NCT01542645 · ClinicalTrials.gov registry record · Phase 4
The Effect of Choice of Intraoperative Opioid on Postoperative Pain
A Phase 4 study, sponsored by Endeavor Health.
- Completed
- Registry status
- Phase 4
- Development phase
- 164
- Enrollment target
NCT01542645: Completed Phase 4 study, sponsored by Endeavor Health.
NCT01542645 is a Phase 4 study that has completed, run by Endeavor Health. The registered enrollment target is 164 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01542645, a Phase 4 study, has completed, sponsored by Endeavor Health.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 164 participants
- Enrollment target
Study Summary
The primary aim of this randomized, double-blind study is to examine the effect of a single intraoperative dose of methadone on postoperative pain and analgesic requirements in patients undergoing cardiac surgery with cardiopulmonary bypass. These patients will be compared to subjects receiving a standard dose of the "traditional" intraoperative opioid (fentanyl). Secondary outcome measures to be assessed will include standard recovery variables (such as length of postoperative intubation, ICU length of stay, incidence of nausea or vomiting, level of sedation). In addition, patients will be assessed for the development of chronic postoperative pain.
Primary Outcome
Total intravenous morphine used first three days (72 hours after ICU admission)
Interventions
- DRUG Methadone
- DRUG Fentanyl
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 164 participants |
| Start Date | 2010-09 |
| Est. Completion | 2014-09 |
| Phase | Phase 4 |
What the finished NCT01542645 record still lists
NCT01542645 is an interventional study that assigns participants to a tested intervention. The registered 164 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 2 interventions - of which Methadone is the first listed.
NCT01542645 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01542645 about?
NCT01542645 is a clinical study titled "The Effect of Choice of Intraoperative Opioid on Postoperative Pain". The primary aim of this randomized, double-blind study is to examine the effect of a single intraoperative dose of methadone on postoperative pain and analgesic requirements in patients undergoing cardiac surgery with cardiopulmonary bypass. These patients will be compared to subjects receiving a st...
What is the current status of trial NCT01542645?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 164 participants. The study started on 2010-09. Estimated completion is 2014-09.
What interventions are being tested in trial NCT01542645?
The interventions under investigation include: Methadone (DRUG), Fentanyl (DRUG).
Who is sponsoring clinical trial NCT01542645?
This trial is sponsored by Endeavor Health, which has 94 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01542645's enrollment target sits among peer trials
164 496th of 2000 higher than 1,500 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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