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NCT01535885 · ClinicalTrials.gov registry record · Phase 1

Using Multi-virus Cytotoxic T-cells Following T-Cell Depleted Allogeneic HPCT for Prophylaxis Against EBV, ADV, and CMV

A Phase 1 study, sponsored by Medical College of Wisconsin.

Completed
Registry status
Phase 1
Development phase
25
Enrollment target

NCT01535885 is a Phase 1 study that has completed, run by Medical College of Wisconsin. The registered enrollment target is 25 participants.

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The verdict

NCT01535885, a Phase 1 study, has completed, sponsored by Medical College of Wisconsin.

COMPLETED
Registry status
Phase 1
Development phase
25 participants
Enrollment target

Study Summary

This protocol is a phase I study. Patients may be eligible for an infusion of Multi-virus Cytotoxic T Lymphocytes (CTL) if they received a T-cell depleted (TCD) transplant from a related family member or an unrelated donor. Recipients of these types of transplants are severely immune compromised during the early post-transplant period and are more susceptible to certain viruses. The investigators hypothesize that the adoptive transfer of Cytotoxic T Lymphocytes (CTL) against certain viruses: Adenovirus, Cytomegalovirus and Epstein Barr Virus (Ad, CMV, and EBV) will be safe with regard to producing graft versus host disease (GVHD) or other infusion related toxicities.

Interventions

  • BIOLOGICAL Cytotoxic T Lymphocytes

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2012-02
Est. Completion 2019-10
Phase Phase 1

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT01535885

The ClinicalTrials.gov registry entry for NCT01535885 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Cytotoxic T Lymphocytes is the first listed.

NCT01535885 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01535885 about?

NCT01535885 is a clinical study titled "Using Multi-virus Cytotoxic T-cells Following T-Cell Depleted Allogeneic HPCT for Prophylaxis Against EBV, ADV, and CMV". This protocol is a phase I study. Patients may be eligible for an infusion of Multi-virus Cytotoxic T Lymphocytes (CTL) if they received a T-cell depleted (TCD) transplant from a related family member or an unrelated donor. Recipients of these types of transplants are severely immune compromised dur...

What is the current status of trial NCT01535885?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2012-02. Estimated completion is 2019-10.

What interventions are being tested in trial NCT01535885?

The interventions under investigation include: Cytotoxic T Lymphocytes (BIOLOGICAL).

Who is sponsoring clinical trial NCT01535885?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.