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NCT01526070 · ClinicalTrials.gov registry record

Study of Bimonthly VEGF Trap-Eye Compared to As-needed Administration or Other Therapy for Exudative Age-Related Macular Degeneration

A clinical trial of Exudative Age-Related Macular Degeneration, sponsored by Stanford University.

Completed
Registry status
142
Enrollment target
1
Study location

NCT01526070 is a study of Exudative Age-Related Macular Degeneration that has completed, run by Stanford University. The registered enrollment target is 142 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT01526070, a study of Exudative Age-Related Macular Degeneration, has completed, sponsored by Stanford University.

COMPLETED
Registry status
142 participants
Enrollment target
1
Study location

Study Summary

Over the last several years, the standard of care for wet macular degeneration has become treatment with intravitreal injections of ranibizumab (Lucentis, Genentech), administered as frequently as every 4 weeks. In contrast, clinical trials of a soluble VEGF receptor, Aflibercept/VEGF Trap-Eye (Eylea, Regeneron Pharmaceuticals) have demonstrated maintained anatomic and visual improvement with many fewer injections (typically monthly injections for 3 months, followed by every-other-month injections, and as few as 5 injections a year). The purpose of this study is to determine whether patients who have switched from ranibizumab to VEGF Trap-Eye have comparable results.

Interventions

  • DRUG Intravitreal injection of Aflibercept

Study Locations (1)

California

  • Byers Eye Institute at Stanford - Palo Alto

Trial Details

FieldValue
Enrollment Target 142 participants
Start Date 2012-01
Est. Completion 2014-07

Sponsor

Stanford University

1,744 total trials

What the Registry Record Tells You About NCT01526070

The ClinicalTrials.gov registry entry for NCT01526070 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 142 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Exudative Age-Related Macular Degeneration appearing as the primary indexed condition, and to 1 intervention - of which Intravitreal injection of Aflibercept is the first listed.

NCT01526070 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT01526070 about?

NCT01526070 is a clinical study titled "Study of Bimonthly VEGF Trap-Eye Compared to As-needed Administration or Other Therapy for Exudative Age-Related Macular Degeneration". Over the last several years, the standard of care for wet macular degeneration has become treatment with intravitreal injections of ranibizumab (Lucentis, Genentech), administered as frequently as every 4 weeks. In contrast, clinical trials of a soluble VEGF receptor, Aflibercept/VEGF Trap-Eye (Eyle...

What is the current status of trial NCT01526070?

This trial is currently completed. The enrollment target is 142 participants. The study started on 2012-01. Estimated completion is 2014-07.

What conditions does trial NCT01526070 study?

This clinical trial studies the following conditions: Exudative Age-Related Macular Degeneration.

What interventions are being tested in trial NCT01526070?

The interventions under investigation include: Intravitreal injection of Aflibercept (DRUG).

Who is sponsoring clinical trial NCT01526070?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01526070 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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