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NCT01523535 · ClinicalTrials.gov registry record · NA
Repeated Challenge of Insufficient Sleep: Endothelial Effects
A NA study, sponsored by Beth Israel Deaconess Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 168
- Enrollment target
NCT01523535 is a NA study that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 168 participants.
The verdict
NCT01523535, a NA study, has completed, sponsored by Beth Israel Deaconess Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 168 participants
- Enrollment target
Study Summary
The 24-hour-a-day, 7-day a week, work-world arrived within our lifetimes, and is here to stay. Americans are working more and more, frequently at multiple jobs. The pattern of short sleep during the week followed by attempts to recover on the weekend is in common practice, but we know little of the associated health risks. What is the cost in terms of increasing known risk markers for cardiovascular disease, of repeated nights of insufficient sleep, and is this cost compounded with repetition, without adequate recovery? Evidence is accumulating to suggest that short sleep duration is linked to the development of metabolic and inflammation-associated diseases, such as cardiovascular disease. Mechanisms involved in the development of cardiovascular disease include impaired vascular function and inflammation. The current proposal is designed to investigate the effects of repeated periods of short nocturnal sleep duration in 4 cycles (each cycle consisting of 3 nights of 4 hours of sleep opportunity per night), and each cycle of short sleep followed by a single night of recovery sleep. Vascular reactivity will be assessed using brachial artery flow mediated dilation, and microcirculatory vasodilation will be assessed using perfusion imaging techniques. The dependence of IL-6 and sVCAM-1 as measured in peripheral circulation, on vascular function, will also be investigated.
Interventions
- BEHAVIORAL repeated cycles of short sleep
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 168 participants |
| Start Date | 2011-08 |
| Est. Completion | 2014-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01523535
The ClinicalTrials.gov registry entry for NCT01523535 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 168 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which repeated cycles of short sleep is the first listed.
NCT01523535 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01523535 about?
NCT01523535 is a clinical study titled "Repeated Challenge of Insufficient Sleep: Endothelial Effects". The 24-hour-a-day, 7-day a week, work-world arrived within our lifetimes, and is here to stay. Americans are working more and more, frequently at multiple jobs. The pattern of short sleep during the week followed by attempts to recover on the weekend is in common practice, but we know little of the ...
What is the current status of trial NCT01523535?
This trial is currently completed. It is a NA study. The enrollment target is 168 participants. The study started on 2011-08. Estimated completion is 2014-09.
What interventions are being tested in trial NCT01523535?
The interventions under investigation include: repeated cycles of short sleep (BEHAVIORAL).
Who is sponsoring clinical trial NCT01523535?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
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