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NCT01522950 · ClinicalTrials.gov registry record · Phase 2
A Study Examining the Effects of Nebivolol Compared to Atenolol on Endothelial Function
A Phase 2 study, sponsored by University of Minnesota.
- Completed
- Registry status
- Phase 2
- Development phase
- 76
- Enrollment target
NCT01522950: Completed Phase 2 study, sponsored by University of Minnesota.
NCT01522950 is a Phase 2 study that has completed, run by University of Minnesota. The registered enrollment target is 76 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01522950, a Phase 2 study, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 76 participants
- Enrollment target
Study Summary
This is a randomized, double-blind, placebo-controlled study comparing the efficacy of nebivolol and atenolol at improving small artery elasticity and reducing cardiovascular disease risk in subjects with early vascular disease. Approximately 75 subjects with borderline/elevated blood pressures and impaired endothelial function, as measured by arterial elasticity scores, will be recruited and assigned to treatment groups using a block randomization scheme. Patients will be randomly allocated to nebivolol, atenolol or placebo, and then followed for 9 months.
Primary Outcome
Change in small artery elasticity (a marker for endothelial function) from baseline to 9 months after intervention initiation.
Interventions
- DRUG placebo
- DRUG Nebivolol
- DRUG atenolol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2010-05 |
| Est. Completion | 2016-10 |
| Phase | Phase 2 |
What the finished NCT01522950 record still lists
NCT01522950 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (43% lower).
The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.
NCT01522950 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01522950 about?
NCT01522950 is a clinical study titled "A Study Examining the Effects of Nebivolol Compared to Atenolol on Endothelial Function". This is a randomized, double-blind, placebo-controlled study comparing the efficacy of nebivolol and atenolol at improving small artery elasticity and reducing cardiovascular disease risk in subjects with early vascular disease. Approximately 75 subjects with borderline/elevated blood pressures and ...
What is the current status of trial NCT01522950?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 76 participants. The study started on 2010-05. Estimated completion is 2016-10.
What interventions are being tested in trial NCT01522950?
The interventions under investigation include: placebo (DRUG), Nebivolol (DRUG), atenolol (DRUG).
Who is sponsoring clinical trial NCT01522950?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01522950's enrollment target sits among peer trials
76 893rd of 2000 higher than 1,101 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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