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NCT01519232 · ClinicalTrials.gov registry record
A Study of Changes in Hepatic Function During Radiation Therapy Using Hepatobiliary Single Photon Emission Tomography (SPECT)
A clinical trial, sponsored by University of Michigan Rogel Cancer Center.
- Completed
- Registry status
- 23
- Enrollment target
NCT01519232: Completed study, sponsored by University of Michigan Rogel Cancer Center.
NCT01519232 is a clinical trial that has completed, run by University of Michigan Rogel Cancer Center. The registered enrollment target is 23 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01519232 has completed, sponsored by University of Michigan Rogel Cancer Center.
- COMPLETED
- Registry status
- 23 participants
- Enrollment target
Study Summary
Radiation-induced liver disease (RILD) is a syndrome characterized by the development of anicteric ascites approximately 2 weeks to 4 months after hepatic irradiation. Previous studies have shown that both the volume of liver irradiated and the dose of radiation delivered are prominent factors for development of RILD. While use of a population-based normal tissue complication probability model allows investigators to limit the risk of RILD to a clinically acceptable level, a test that permits investigators to determine an individual's risk of RILD during the course of treatment may allow for individualized treatment modifications, either to prevent toxicity or increase efficacy.
Primary Outcome
Changes in SPECT, which reflect hepatocyte function, will be correlated with specific regions of radiation dose to determine a relationship between dose and radiation-induced damage.
Interventions
- RADIATION Liver Irradiation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2008-08 |
| Est. Completion | 2014-05 |
What the finished NCT01519232 record still lists
NCT01519232 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 23 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Liver Irradiation is the first listed.
NCT01519232 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01519232 about?
NCT01519232 is a clinical study titled "A Study of Changes in Hepatic Function During Radiation Therapy Using Hepatobiliary Single Photon Emission Tomography (SPECT)". Radiation-induced liver disease (RILD) is a syndrome characterized by the development of anicteric ascites approximately 2 weeks to 4 months after hepatic irradiation. Previous studies have shown that both the volume of liver irradiated and the dose of radiation delivered are prominent factors for d...
What is the current status of trial NCT01519232?
This trial is currently completed. The enrollment target is 23 participants. The study started on 2008-08. Estimated completion is 2014-05.
What interventions are being tested in trial NCT01519232?
The interventions under investigation include: Liver Irradiation (RADIATION).
Who is sponsoring clinical trial NCT01519232?
This trial is sponsored by University of Michigan Rogel Cancer Center, which has 292 total clinical trials registered on ClinicalTrials.gov.
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