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NCT01516957 · ClinicalTrials.gov registry record · Phase 2
AMG 827 in Subjects With Psoriatic Arthritis
A Phase 2 study, sponsored by Bausch Health Americas.
- Terminated
- Registry status
- Phase 2
- Development phase
- 168
- Enrollment target
NCT01516957: Clinical Trial Phase 2 study, sponsored by Bausch Health Americas.
NCT01516957 is a Phase 2 study that was terminated before completion, run by Bausch Health Americas. The registered enrollment target is 168 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (26% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01516957, a Phase 2 study, was terminated before completion, sponsored by Bausch Health Americas.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 168 participants
- Enrollment target
Study Summary
The study will examine the safety and effectiveness of AMG 827 for the treatment of psoriatic arthritis
Primary Outcome
To evaluate the efficacy of AMG 827 in psoriatic arthritis as measured by the proportion of subjects achieving an American College of Rheumatology (ACR) 20% response at week 12. ACR20 responders are subjects with 20% improvement from baseline based off of percent changes in tender/painful joint count, swollen joint counts, physician global assessment of disease activity, and health assessment questionnaire-disability index.
Interventions
- DRUG Placebo
- DRUG AMG 827 140
- DRUG AMG 827 280
- DRUG AMG 827 210
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 168 participants |
| Start Date | 2011-10 |
| Est. Completion | 2015-09 |
| Phase | Phase 2 |
Why NCT01516957 stopped before completion
NCT01516957 is an interventional study that assigns participants to a tested intervention. The registered 168 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (26% higher).
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT01516957 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01516957 about?
NCT01516957 is a clinical study titled "AMG 827 in Subjects With Psoriatic Arthritis". The study will examine the safety and effectiveness of AMG 827 for the treatment of psoriatic arthritis
What is the current status of trial NCT01516957?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 168 participants. The study started on 2011-10. Estimated completion is 2015-09.
What interventions are being tested in trial NCT01516957?
The interventions under investigation include: Placebo (DRUG), AMG 827 140 (DRUG), AMG 827 280 (DRUG), AMG 827 210 (DRUG).
Who is sponsoring clinical trial NCT01516957?
This trial is sponsored by Bausch Health Americas, which has 168 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01516957's enrollment target sits among peer trials
168 403rd of 2000 higher than 1,595 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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