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NCT01516918 · ClinicalTrials.gov registry record · Phase 2
A Study to Evaluate the Efficacy and Safety of Quadruple Therapy (VX-222, Telaprevir,Peginterferon-Alfa-2a, Ribavirin) in Subjects With Chronic Hepatitis C With Compensated Cirrhosis
A Phase 2 study, sponsored by Vertex Pharmaceuticals Incorporated.
- Completed
- Registry status
- Phase 2
- Development phase
- 103
- Enrollment target
NCT01516918: Completed Phase 2 study, sponsored by Vertex Pharmaceuticals Incorporated.
NCT01516918 is a Phase 2 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 103 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01516918, a Phase 2 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 103 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the safety and efficacy of a quadruple regimen (VX-222, telaprevir, pegylated interferon, and ribavirin)in subjects with hepatitis C with cirrhosis.
Interventions
- DRUG ribavirin
- DRUG telaprevir
- DRUG VX-222
- BIOLOGICAL peginterferon-alfa-2a
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 103 participants |
| Start Date | 2012-02 |
| Est. Completion | 2013-12 |
| Phase | Phase 2 |
What the finished NCT01516918 record still lists
NCT01516918 is an interventional study that assigns participants to a tested intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% lower).
The record links to 0 conditions, and to 4 interventions - of which ribavirin is the first listed.
NCT01516918 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01516918 about?
NCT01516918 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Quadruple Therapy (VX-222, Telaprevir,Peginterferon-Alfa-2a, Ribavirin) in Subjects With Chronic Hepatitis C With Compensated Cirrhosis". The purpose of this study is to evaluate the safety and efficacy of a quadruple regimen (VX-222, telaprevir, pegylated interferon, and ribavirin)in subjects with hepatitis C with cirrhosis.
What is the current status of trial NCT01516918?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 103 participants. The study started on 2012-02. Estimated completion is 2013-12.
What interventions are being tested in trial NCT01516918?
The interventions under investigation include: ribavirin (DRUG), telaprevir (DRUG), VX-222 (DRUG), peginterferon-alfa-2a (BIOLOGICAL).
Who is sponsoring clinical trial NCT01516918?
This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01516918's enrollment target sits among peer trials
103 664th of 2000 higher than 1,333 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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