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NCT01501929 · ClinicalTrials.gov registry record · Phase 4

Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients

A Phase 4 study, sponsored by University of Texas Southwestern Medical Center.

Completed
Registry status
Phase 4
Development phase
32
Enrollment target

NCT01501929 is a Phase 4 study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 32 participants.

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The verdict

NCT01501929, a Phase 4 study, has completed, sponsored by University of Texas Southwestern Medical Center.

COMPLETED
Registry status
Phase 4
Development phase
32 participants
Enrollment target

Study Summary

The purpose of this study is to determine if Nebivolol improves microvascular perfusion in skeletal muscle during exercise in hypertensive patients and whether this improvement is accompanied by reduction in vascular oxidative stress or increased endothelial nitric oxide synthase (eNOS) expression in humans.

Interventions

  • DRUG Nebivolol
  • DRUG Metoprolol succinate
  • PROCEDURE Non-invasive measurement of Cardiac Output (CO)
  • PROCEDURE Endothelial cell collection
  • PROCEDURE Microvascular perfusion assessment using Definity

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2010-08
Est. Completion 2015-12
Phase Phase 4

What the Registry Record Tells You About NCT01501929

The ClinicalTrials.gov registry entry for NCT01501929 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Nebivolol is the first listed.

NCT01501929 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01501929 about?

NCT01501929 is a clinical study titled "Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients". The purpose of this study is to determine if Nebivolol improves microvascular perfusion in skeletal muscle during exercise in hypertensive patients and whether this improvement is accompanied by reduction in vascular oxidative stress or increased endothelial nitric oxide synthase (eNOS) expression i...

What is the current status of trial NCT01501929?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 32 participants. The study started on 2010-08. Estimated completion is 2015-12.

What interventions are being tested in trial NCT01501929?

The interventions under investigation include: Nebivolol (DRUG), Metoprolol succinate (DRUG), Non-invasive measurement of Cardiac Output (CO) (PROCEDURE), Endothelial cell collection (PROCEDURE), Microvascular perfusion assessment using Definity (PROCEDURE).

Who is sponsoring clinical trial NCT01501929?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.