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NCT01493869 · ClinicalTrials.gov registry record · Phase 1

Study to Assess the Pharmacokinetics of Cabozantinib (XL184) in Hepatic Impaired Adult Subjects

A Phase 1 study, sponsored by Exelixis.

Completed
Registry status
Phase 1
Development phase
26
Enrollment target

NCT01493869 is a Phase 1 study that has completed, run by Exelixis. The registered enrollment target is 26 participants.

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The verdict

NCT01493869, a Phase 1 study, has completed, sponsored by Exelixis.

COMPLETED
Registry status
Phase 1
Development phase
26 participants
Enrollment target

Study Summary

The main objective of this study is to compare the pharmacokinetics (PK) of a single oral 75 mg dose of cabozantinib in hepatic impaired adult subjects to healthy adult subjects. Another objective is to assess the safety and tolerability of cabozantinib in these adult subjects.

Interventions

  • DRUG cabozantinib

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2011-09
Est. Completion 2014-08
Phase Phase 1

Sponsor

Exelixis

48 total trials

What the Registry Record Tells You About NCT01493869

The ClinicalTrials.gov registry entry for NCT01493869 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Exelixis, which has 48 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which cabozantinib is the first listed.

NCT01493869 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01493869 about?

NCT01493869 is a clinical study titled "Study to Assess the Pharmacokinetics of Cabozantinib (XL184) in Hepatic Impaired Adult Subjects". The main objective of this study is to compare the pharmacokinetics (PK) of a single oral 75 mg dose of cabozantinib in hepatic impaired adult subjects to healthy adult subjects. Another objective is to assess the safety and tolerability of cabozantinib in these adult subjects.

What is the current status of trial NCT01493869?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2011-09. Estimated completion is 2014-08.

What interventions are being tested in trial NCT01493869?

The interventions under investigation include: cabozantinib (DRUG).

Who is sponsoring clinical trial NCT01493869?

This trial is sponsored by Exelixis, which has 48 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.