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NCT01492426 · ClinicalTrials.gov registry record · Phase 3
Study Comparing Daclatasvir (BMS-790052) With Telaprevir Combined With Peginterferon Alfa-2a and Ribavirin in Patients With Chronic Hepatitis C Virus Infection
A Phase 3 study of Hepatitis C, sponsored by Bristol-Myers Squibb.
- Completed
- Registry status
- Phase 3
- Development phase
- 605
- Enrollment target
- 20
- Study locations
NCT01492426: Completed Phase 3 study of Hepatitis C, sponsored by Bristol-Myers Squibb.
NCT01492426 is a Phase 3 study of Hepatitis C that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 605 participants, below the 1,884-participant average among 106 other Hepatitis C trials with a reported enrollment target (68% lower). The trial reports 20 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01492426, a Phase 3 study of Hepatitis C, has completed, sponsored by Bristol-Myers Squibb.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 605 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to compare the effectiveness of BMS-790052 (Daclatasvir) and Telaprevir when given in combination with Peginterferon alfa-2a and Ribavirin in genotype 1b patients
Primary Outcome
SVR12 was defined as hepatitis C virus RNA levels to be lower than the limit of quantitation, ie, 25 IU/mL target detected or target not detected at follow-up Week 12.
Conditions Studied
Interventions
- DRUG Ribavirin
- DRUG Daclatasvir
- DRUG Peginterferon alfa-2a
- DRUG Telaprevir
Study Locations (20)
North Carolina
- University Of North Carolina At Chapel Hill School Of Med - Chapel Hill
- Carolinas Medical Center - Charlotte
- Duke University Medical Center - Durham
California
- Va Long Beach Healthcare System - Long Beach
- Medical Associates Research Group - San Diego
Georgia
- Atlanta Medical Center - Atlanta
- Gastrointestinal Specialists Of Georgia - Marietta
Illinois
- Northwestern University - Chicago
- Rush University Medical Center - Chicago
Maryland
- University Of Maryland - Baltimore
- Johns Hopkins University - Lutherville
Alabama
- The Kirklin Clinic - Birmingham
Arizona
- Mayo Clinic Arizona - Phoenix
Connecticut
- Yale University School Of Medicine - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 605 participants |
| Start Date | 2012-01 |
| Est. Completion | 2014-03 |
| Phase | Phase 3 |
What the finished NCT01492426 record still lists
NCT01492426 is an interventional study that assigns participants to a tested intervention. The registered 605 participants enrollment target is mid-sized for trials with a published cap, below the 1,884-participant average among 106 other Hepatitis C trials with a reported enrollment target (68% lower).
The record links to 1 condition, with Hepatitis C appearing as the primary indexed condition, and to 4 interventions - of which Ribavirin is the first listed.
NCT01492426 names 20 study sites across 14 states, led by North Carolina, California, Georgia.
Frequently Asked Questions
What is clinical trial NCT01492426 about?
NCT01492426 is a clinical study titled "Study Comparing Daclatasvir (BMS-790052) With Telaprevir Combined With Peginterferon Alfa-2a and Ribavirin in Patients With Chronic Hepatitis C Virus Infection". The purpose of this study is to compare the effectiveness of BMS-790052 (Daclatasvir) and Telaprevir when given in combination with Peginterferon alfa-2a and Ribavirin in genotype 1b patients
What is the current status of trial NCT01492426?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 605 participants. The study started on 2012-01. Estimated completion is 2014-03.
What conditions does trial NCT01492426 study?
This clinical trial studies the following conditions: Hepatitis C.
What interventions are being tested in trial NCT01492426?
The interventions under investigation include: Ribavirin (DRUG), Daclatasvir (DRUG), Peginterferon alfa-2a (DRUG), Telaprevir (DRUG).
Who is sponsoring clinical trial NCT01492426?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01492426 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hepatitis C
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01492426's enrollment target sits among peer trials
605 15th of 106 higher than 92 of 106 other Hepatitis C trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hepatitis C trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Efficacy and Safety of BI 201335 (Faldaprevir) in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-naïve Genotype 1 Hepatitis C Infected Patients (STARTverso 2)
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