Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01484470 · ClinicalTrials.gov registry record · Phase 2
Umbilical Cord Transplantation for the Elderly Population
A Phase 2 study, sponsored by Loyola University.
- Completed
- Registry status
- Phase 2
- Development phase
- 18
- Enrollment target
NCT01484470: Completed Phase 2 study, sponsored by Loyola University.
NCT01484470 is a Phase 2 study that has completed, run by Loyola University. The registered enrollment target is 18 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01484470, a Phase 2 study, has completed, sponsored by Loyola University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 18 participants
- Enrollment target
Study Summary
While cord blood transplants have been performed safely in elderly patients, many still relapse. The investigators propose to intensify the preparative regimen for this patient group in an attempt to decrease relapses, and combine this with an ex vivo expanded Umbilical Cord Blood (UCB) unit.
Primary Outcome
The primary endpoint is to demonstrate the efficacy of StemEx® vs. unmanipulated UCB transplantation in the elderly population (\>55years of age) following RIC regimen by demonstrating engraftment with full donor chimerism (\>98%) by Day 100 of more than 60% of the patients who received transplants expanded by the StemEx method.
Interventions
- BIOLOGICAL StemEx
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2010-01 |
| Est. Completion | 2018-11-21 |
| Phase | Phase 2 |
What the finished NCT01484470 record still lists
NCT01484470 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 1 intervention - of which StemEx is the first listed.
NCT01484470 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01484470 about?
NCT01484470 is a clinical study titled "Umbilical Cord Transplantation for the Elderly Population". While cord blood transplants have been performed safely in elderly patients, many still relapse. The investigators propose to intensify the preparative regimen for this patient group in an attempt to decrease relapses, and combine this with an ex vivo expanded Umbilical Cord Blood (UCB) unit.
What is the current status of trial NCT01484470?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2010-01. Estimated completion is 2018-11-21.
What interventions are being tested in trial NCT01484470?
The interventions under investigation include: StemEx (BIOLOGICAL).
Who is sponsoring clinical trial NCT01484470?
This trial is sponsored by Loyola University, which has 92 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01484470's enrollment target sits among peer trials
18 1898th of 2000 higher than 98 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01245179 · 18 participants · Phase 1
Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease
- NCT01999361 · 18 participants · NA
Prevention of de Novo Allosensitization in Islet Transplant Recipients Following Complete Graft Loss
- NCT02359825 · 18 participants · Phase 1
Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function
- NCT02870244 · 18 participants · Phase 1
Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia