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NCT01475500 · ClinicalTrials.gov registry record
Nashville Early Diagnosis Lung Cancer Project
A clinical trial of Lung Cancer, sponsored by Vanderbilt-Ingram Cancer Center.
- Active
- Registry status
- 480
- Enrollment target
- 2
- Study locations
NCT01475500: Active study of Lung Cancer, sponsored by Vanderbilt-Ingram Cancer Center.
NCT01475500 is a study of Lung Cancer that is active but no longer recruiting, run by Vanderbilt-Ingram Cancer Center. The registered enrollment target is 480 participants, below the 935-participant average among 409 other Lung Cancer trials with a reported enrollment target (49% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01475500, a study of Lung Cancer, is active but no longer recruiting, sponsored by Vanderbilt-Ingram Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- 480 participants
- Enrollment target
- 2
- Study locations
Study Summary
This screening study will address the lack of molecular strategies for the early detection of lung cancer and integrate those with epidemiological and imaging strategies. The hypothesis is that the repeated measure of biomarkers of risk obtained from the molecular analysis of biological specimens including those from bronchoscopy (bronchial brushings and biopsies) may contribute to the refinement of high-risk populations and allow an earlier clinical diagnosis. The goal of the investigators study is to provide screening for lung cancer in a high-risk population. In this prospective cohort it will be tested whether repeated measure of biomarkers of risk allows early detection of lung cancer.
Primary Outcome
Blood, sputum, urine, nasal washings, buccal epithelium, endobronchial tissue, and bronchioalveolar washings are examined for biomarkers present in patients who develop lung cancer compared with those patients who do not develop lung cancer. Baseline and yearly screening results will be compared in the two groups.
Conditions Studied
Interventions
- PROCEDURE Sputum sample
- PROCEDURE Pulmonary function tests
- RADIATION Computerized tomography (CT) scan of the chest
- OTHER Buccal epithelium collection
- PROCEDURE Nasal brushings
Study Locations (2)
Tennessee
- Veterans Administration - Nashville
- Vanderbilt University, Vanderbilt-Ingram Cancer Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 480 participants |
| Start Date | 2011-04 |
| Est. Completion | 2026-11-30 |
What the registry record for NCT01475500 still lists
NCT01475500 is an observational study that tracks outcomes without assigning an intervention. The registered 480 participants enrollment target is mid-sized for trials with a published cap, below the 935-participant average among 409 other Lung Cancer trials with a reported enrollment target (49% lower).
The record links to 1 condition, with Lung Cancer appearing as the primary indexed condition, and to 5 interventions - of which Sputum sample is the first listed.
NCT01475500 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT01475500 about?
NCT01475500 is a clinical study titled "Nashville Early Diagnosis Lung Cancer Project". This screening study will address the lack of molecular strategies for the early detection of lung cancer and integrate those with epidemiological and imaging strategies. The hypothesis is that the repeated measure of biomarkers of risk obtained from the molecular analysis of biological specimens i...
What is the current status of trial NCT01475500?
This trial is currently active not recruiting. The enrollment target is 480 participants. The study started on 2011-04. Estimated completion is 2026-11-30.
What conditions does trial NCT01475500 study?
This clinical trial studies the following conditions: Lung Cancer.
What interventions are being tested in trial NCT01475500?
The interventions under investigation include: Sputum sample (PROCEDURE), Pulmonary function tests (PROCEDURE), Computerized tomography (CT) scan of the chest (RADIATION), Buccal epithelium collection (OTHER), Nasal brushings (PROCEDURE).
Who is sponsoring clinical trial NCT01475500?
This trial is sponsored by Vanderbilt-Ingram Cancer Center, which has 189 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01475500 being conducted?
This trial has 2 study locations across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lung Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01475500's enrollment target sits among peer trials
480 75th of 409 higher than 334 of 409 other Lung Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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