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NCT01466088 · ClinicalTrials.gov registry record · Phase 2
Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)
A Phase 2 study of Alzheimers Disease, sponsored by Targacept.
- Completed
- Registry status
- Phase 2
- Development phase
- 386
- Enrollment target
- 20
- Study locations
NCT01466088: Completed Phase 2 study of Alzheimers Disease, sponsored by Targacept.
NCT01466088 is a Phase 2 study of Alzheimers Disease that has completed, run by Targacept. The registered enrollment target is 386 participants, below the 3,924-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (90% lower). The trial reports 20 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01466088, a Phase 2 study of Alzheimers Disease, has completed, sponsored by Targacept.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 386 participants
- Enrollment target
- 20
- Study locations
Study Summary
Alzheimer's disease is the most common form of dementia and is the fourth leading cause of death among people 65 years of age and older. The global prevalence of the disease will increase significantly as the population ages, unless preventative treatments can be identified and marketed. The present study seeks to evaluate AZD3480 (TC-1734) compared to an approved medication (donepezil) shown to improve cognition and function in patients with Alzheimer's disease.
Conditions Studied
Interventions
- DRUG Donepezil
- DRUG AZD3480
Study Locations (20)
Other
- Policlinic - Choceň
- BRAIN-SOULTHERAPY s.r.o. - Kladno
- Bialbi.s.r.o. Psychiatrické oddělení - Litoměřice
- Psychiatricka Ambulance - Olomouc
- Vojenska Nemocnice Psychiatricke oddeleni - Olomouc
- Clintrial - Prague
- PRAGTIS s.r.o. - Prague
- Psychosocialni centrum - Přerov
- Crucea Alba - Dr. Oros si Asociatii - Societate Civila Medicala - Oradea
- Spitalul de Psihiatrie Sibiu - Sibiu
- Spitalul Clinic Judetean de Urgenta SIBIU - Sibiu
- Spitalul Clinic Judetean de Urgenta, Clinica Psihiatrie - Timișoara
- Spitalul Clinic Judetean de Urgenta, Clinica Neurologie 2 - Timișoara
- Neurologicka Ambulancia, s.r.o. - Banská Bystrica
- Univerzitna nemocnica Bratislava, Geronto-psychiatrické oddelenie - Bratislava
- KONZILIUM s.r.o. - Dubnica nad Váhom
- Neurologická ambulancia - Krompachy
Florida
- Meridien Research - Brooksville
- MD Clinical - Hallandale
Arizona
- Banner Alzheimer Institute - Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 386 participants |
| Start Date | 2011-10 |
| Est. Completion | 2014-05 |
| Phase | Phase 2 |
What the finished NCT01466088 record still lists
NCT01466088 is an interventional study that assigns participants to a tested intervention. The registered 386 participants enrollment target is mid-sized for trials with a published cap, below the 3,924-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Alzheimers Disease appearing as the primary indexed condition, and to 2 interventions - of which Donepezil is the first listed.
NCT01466088 names 20 study sites across 3 states, led by Other, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT01466088 about?
NCT01466088 is a clinical study titled "Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)". Alzheimer's disease is the most common form of dementia and is the fourth leading cause of death among people 65 years of age and older. The global prevalence of the disease will increase significantly as the population ages, unless preventative treatments can be identified and marketed. The present...
What is the current status of trial NCT01466088?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 386 participants. The study started on 2011-10. Estimated completion is 2014-05.
What conditions does trial NCT01466088 study?
This clinical trial studies the following conditions: Alzheimers Disease.
What interventions are being tested in trial NCT01466088?
The interventions under investigation include: Donepezil (DRUG), AZD3480 (DRUG).
Who is sponsoring clinical trial NCT01466088?
This trial is sponsored by Targacept, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01466088 being conducted?
This trial has 20 study locations across Arizona, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alzheimers Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01466088's enrollment target sits among peer trials
386 36th of 147 higher than 112 of 147 other Alzheimers Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimers Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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