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NCT01440972 · ClinicalTrials.gov registry record · NA
Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis
A NA study, sponsored by University of Iowa.
- Completed
- Registry status
- NA
- Development phase
- 45
- Enrollment target
NCT01440972: Completed NA study, sponsored by University of Iowa.
NCT01440972 is a NA study that has completed, run by University of Iowa. The registered enrollment target is 45 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01440972, a NA study, has completed, sponsored by University of Iowa.
- COMPLETED
- Registry status
- NA
- Development phase
- 45 participants
- Enrollment target
Study Summary
The purpose of this study is to asses the efficacy of a 4 week low-intensity resistance training program with concurrent application of partial blood flow restriction (PBFR) to the exercising limbs to improve quadriceps strength and size, leg muscle power, and mobility in women at risk for developing symptomatic knee osteoarthritis. The primary outcome will be change in isotonic double leg-press 1 repetition maximum (1RM) strength. The investigators will test the following hypotheses. In comparison with low-intensity resistance training without use of PBFR, a four-week low-intensity resistance-training program with PBFR will: Primary Hypothesis: Increase (a) double leg-press 1RM strength and (b) isokinetic knee extensor strength Secondary Hypotheses: 1. Increase quadriceps muscle volume assessed by MRI 2. Increase lower limb muscle power on (a) double leg-press at 40% 1RM and (b) a timed stair climb 3. Not adversely effect knee pain or quality of life assessed by the Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaire
Interventions
- OTHER partial blood flow restriction (PBFR)
- OTHER low intensity resistance training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2011-09 |
| Est. Completion | 2011-11 |
| Phase | NA |
What the finished NCT01440972 record still lists
NCT01440972 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which partial blood flow restriction (PBFR) is the first listed.
NCT01440972 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01440972 about?
NCT01440972 is a clinical study titled "Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis". The purpose of this study is to asses the efficacy of a 4 week low-intensity resistance training program with concurrent application of partial blood flow restriction (PBFR) to the exercising limbs to improve quadriceps strength and size, leg muscle power, and mobility in women at risk for developin...
What is the current status of trial NCT01440972?
This trial is currently completed. It is a NA study. The enrollment target is 45 participants. The study started on 2011-09. Estimated completion is 2011-11.
What interventions are being tested in trial NCT01440972?
The interventions under investigation include: partial blood flow restriction (PBFR) (OTHER), low intensity resistance training (OTHER).
Who is sponsoring clinical trial NCT01440972?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01440972's enrollment target sits among peer trials
45 1411th of 2000 higher than 578 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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