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NCT01440881 · ClinicalTrials.gov registry record · Phase 2
Does Nesiritide Provide Renal Protection
A Phase 2 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 2
- Development phase
- 37
- Enrollment target
NCT01440881: Completed Phase 2 study, sponsored by University of Florida.
NCT01440881 is a Phase 2 study that has completed, run by University of Florida. The registered enrollment target is 37 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01440881, a Phase 2 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 37 participants
- Enrollment target
Study Summary
This project evaluates whether nesiritide, human recombinant brain natriuretic peptide, confers renal protection during cardiovascular surgery by attenuating the inflammatory response.
Primary Outcome
0.35 mL of whole blood from each patient was applied to a microfluidics chip to isolate neutrophils. Total RNA was subsequently isolated and gene expression (for all genes listed below) was measured with an Affymetrix gene chip. Data was normalized using RMA (Robust multi-array average) and expressed as log2 expression.
Interventions
- DRUG Placebo
- DRUG Nesiritide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2010-04 |
| Est. Completion | 2012-12 |
| Phase | Phase 2 |
What the finished NCT01440881 record still lists
NCT01440881 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01440881 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01440881 about?
NCT01440881 is a clinical study titled "Does Nesiritide Provide Renal Protection". This project evaluates whether nesiritide, human recombinant brain natriuretic peptide, confers renal protection during cardiovascular surgery by attenuating the inflammatory response.
What is the current status of trial NCT01440881?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 37 participants. The study started on 2010-04. Estimated completion is 2012-12.
What interventions are being tested in trial NCT01440881?
The interventions under investigation include: Placebo (DRUG), Nesiritide (DRUG).
Who is sponsoring clinical trial NCT01440881?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01440881's enrollment target sits among peer trials
37 1484th of 2000 higher than 505 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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