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NCT01437995 · ClinicalTrials.gov registry record · Phase 4

Long-acting Beta Agonist Step Down Study

A Phase 4 study, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 4
Development phase
459
Enrollment target

NCT01437995: Completed Phase 4 study, sponsored by Johns Hopkins University.

NCT01437995 is a Phase 4 study that has completed, run by Johns Hopkins University. The registered enrollment target is 459 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (11% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01437995, a Phase 4 study, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 4
Development phase
459 participants
Enrollment target

Study Summary

This study is a 56-week, multi-center, blinded, randomized, double-masked parallel group comparative effectiveness study of approaches to stepping down therapy for patients with well-controlled asthma treated with combination ICS and LABA.

Primary Outcome

Rate of treatment failures assessed by decline in peak flow or FEV1, increased need for beta agonists, requirement for non-scheduled medical care for asthma symptoms, or prednisone taper.

Interventions

  • DRUG Fluticasone/Salmeterol Diskus
  • DRUG Fluticasone Diskus

Trial Details

FieldValue
Enrollment Target 459 participants
Start Date 2012-03
Est. Completion 2015-10
Phase Phase 4
Johns Hopkins University

1,448 total trials

What the finished NCT01437995 record still lists

NCT01437995 is an interventional study that assigns participants to a tested intervention. The registered 459 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (11% lower).

The record links to 0 conditions, and to 2 interventions - of which Fluticasone/Salmeterol Diskus is the first listed.

NCT01437995 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01437995 about?

NCT01437995 is a clinical study titled "Long-acting Beta Agonist Step Down Study". This study is a 56-week, multi-center, blinded, randomized, double-masked parallel group comparative effectiveness study of approaches to stepping down therapy for patients with well-controlled asthma treated with combination ICS and LABA.

What is the current status of trial NCT01437995?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 459 participants. The study started on 2012-03. Estimated completion is 2015-10.

What interventions are being tested in trial NCT01437995?

The interventions under investigation include: Fluticasone/Salmeterol Diskus (DRUG), Fluticasone Diskus (DRUG).

Who is sponsoring clinical trial NCT01437995?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01437995's enrollment target sits among peer trials

459 185th of 2000 higher than 1,816 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01437995, the US trial registry maintained by the National Library of Medicine. NCT01437995 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.