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NCT01428245 · ClinicalTrials.gov registry record · NA

Assessment of Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition

A NA study, sponsored by University of Virginia.

Terminated
Registry status
NA
Development phase
3
Enrollment target

NCT01428245 is a NA study that was terminated before completion, run by University of Virginia. The registered enrollment target is 3 participants.

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The verdict

NCT01428245, a NA study, was terminated before completion, sponsored by University of Virginia.

TERMINATED
Registry status
NA
Development phase
3 participants
Enrollment target

Study Summary

Gonadotropin-releasing hormone (GnRH) is a hormone that regulates the ability of the pituitary to secrete two hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). LH and FSH control the production of female hormones (such as estrogen and progesterone) and the development of eggs by the ovary. Progesterone and estrogen then decrease the number of GnRH pulses produced by the brain (and therefore the number of LH pulses from the pituitary). The ability to decrease GnRH pulses seems to be very important for normal menstrual function in adult women. The purpose of this study is to learn more about how GnRH and LH pulses are controlled during puberty. The information gathered in this study will hopefully allow us to learn more about how menstrual cycles are normally established in girls during puberty.

Interventions

  • DRUG Progesterone
  • DRUG Estrace (estrogen)

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2011-04-22
Est. Completion 2013-05-14
Phase NA

Sponsor

University of Virginia

449 total trials

What the Registry Record Tells You About NCT01428245

The ClinicalTrials.gov registry entry for NCT01428245 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Progesterone is the first listed.

NCT01428245 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01428245 about?

NCT01428245 is a clinical study titled "Assessment of Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition". Gonadotropin-releasing hormone (GnRH) is a hormone that regulates the ability of the pituitary to secrete two hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). LH and FSH control the production of female hormones (such as estrogen and progesterone) and the development of egg...

What is the current status of trial NCT01428245?

This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2011-04-22. Estimated completion is 2013-05-14.

What interventions are being tested in trial NCT01428245?

The interventions under investigation include: Progesterone (DRUG), Estrace (estrogen) (DRUG).

Who is sponsoring clinical trial NCT01428245?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.