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NCT01411852 · ClinicalTrials.gov registry record · Phase 2
Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma
A Phase 2 study, sponsored by University of Washington.
- Completed
- Registry status
- Phase 2
- Development phase
- 192
- Enrollment target
NCT01411852: Completed Phase 2 study, sponsored by University of Washington.
NCT01411852 is a Phase 2 study that has completed, run by University of Washington. The registered enrollment target is 192 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01411852, a Phase 2 study, has completed, sponsored by University of Washington.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 192 participants
- Enrollment target
Study Summary
Primary Aim: To determine the feasibility and safety of hypotensive resuscitation for the early treatment of patients with traumatic shock compared to standard fluid resuscitation. Primary Hypotheses: The null hypothesis regarding feasibility is that hypotensive resuscitation will result in the same volume of early crystalloid (normal saline) fluid administration compared to standard crystalloid resuscitation. The null hypothesis regarding safety is that hypotensive resuscitation will result in the same percent of patients surviving to 24 hours after 911 call received at dispatch compared to standard fluid resuscitation. Early resuscitation is defined as all fluid given until 2 hours after arrival in the Emergency Department or until hemorrhage control is achieved in the hospital, whichever occurs earlier.
Primary Outcome
The primary feasibility endpoint was early crystalloid volume (ECV) defined as crystalloid infused from Emergency Medical Services (EMS) arrival at the scene until the end of the study period
Interventions
- DRUG 0.9% Sodium Chloride 250 mL bolus
- DRUG 0.9% Sodium Chloride 2000 mL bolus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 192 participants |
| Start Date | 2012-03 |
| Est. Completion | 2013-04 |
| Phase | Phase 2 |
What the finished NCT01411852 record still lists
NCT01411852 is an interventional study that assigns participants to a tested intervention. The registered 192 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% higher).
The record links to 0 conditions, and to 2 interventions - of which 0.9% Sodium Chloride 250 mL bolus is the first listed.
NCT01411852 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01411852 about?
NCT01411852 is a clinical study titled "Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma". Primary Aim: To determine the feasibility and safety of hypotensive resuscitation for the early treatment of patients with traumatic shock compared to standard fluid resuscitation. Primary Hypotheses: The null hypothesis regarding feasibility is that hypotensive resuscitation will result in the sam...
What is the current status of trial NCT01411852?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 192 participants. The study started on 2012-03. Estimated completion is 2013-04.
What interventions are being tested in trial NCT01411852?
The interventions under investigation include: 0.9% Sodium Chloride 250 mL bolus (DRUG), 0.9% Sodium Chloride 2000 mL bolus (DRUG).
Who is sponsoring clinical trial NCT01411852?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01411852's enrollment target sits among peer trials
192 352nd of 2000 higher than 1,648 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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