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NCT01403766 · ClinicalTrials.gov registry record
Comparison of Markers of Kidney Function
A clinical trial, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- 17
- Enrollment target
NCT01403766 is a clinical trial that has completed, run by University of California, Los Angeles. The registered enrollment target is 17 participants.
The verdict
NCT01403766 has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- 17 participants
- Enrollment target
Study Summary
Glomerular filtration rate (GFR) is the best known measurement of kidney function. Serum creatinine (blood test) is the most commonly used marker to predict GFR. It is a convenient, inexpensive test that involves a single blood draw with rapid results. However, creatinine has several limitations because its blood level is dependent on age, body mass, and sex. One of the gold standards for measuring GFR is plasma clearance of an IV injected agent, iohexol. It has been found to be safe and nontoxic in prior studies, but is not practical in the clinical setting due to the need for several timed blood draws. Recent studies have investigated the use of cystatin C as an alternative marker to predict GFR. Cystatin C also involves only a single blood draw, and has less confounding factors than creatinine since it is independent of age, body mass, and sex. Currently, it remains controversial whether cystatin C is a significantly better biomarker of estimated GFR than creatinine. To date, there has not been a large prospective cohort study to compare cystatin C and creatinine in pediatric kidney transplant patients who are on maintenance immunosuppression (anti-rejection drugs). Accurate measurement and early detection of deterioration of GFR is critical in the care of this patient population. The purpose of this study is to assess the accuracy of estimating GFR by using cystatin C versus creatinine clearance equations when compared to the surrogate gold standard of iohexol GFR in pediatric renal transplant patients.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2011-08 |
| Est. Completion | 2012-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01403766
The ClinicalTrials.gov registry entry for NCT01403766 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01403766 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01403766 about?
NCT01403766 is a clinical study titled "Comparison of Markers of Kidney Function". Glomerular filtration rate (GFR) is the best known measurement of kidney function. Serum creatinine (blood test) is the most commonly used marker to predict GFR. It is a convenient, inexpensive test that involves a single blood draw with rapid results. However, creatinine has several limitations bec...
What is the current status of trial NCT01403766?
This trial is currently completed. The enrollment target is 17 participants. The study started on 2011-08. Estimated completion is 2012-12.
Who is sponsoring clinical trial NCT01403766?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
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