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NCT01391143 · ClinicalTrials.gov registry record · Phase 1
Safety Study of MGA271 in Refractory Cancer
A Phase 1 study, sponsored by MacroGenics.
- Completed
- Registry status
- Phase 1
- Development phase
- 179
- Enrollment target
NCT01391143: Completed Phase 1 study, sponsored by MacroGenics.
NCT01391143 is a Phase 1 study that has completed, run by MacroGenics. The registered enrollment target is 179 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (198% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01391143, a Phase 1 study, has completed, sponsored by MacroGenics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 179 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the safety of MGA271 when given by intravenous (IV) infusion to patients with refractory cancer. The study will also evaluate how long MGA271 stays in the blood and how long it takes for it to leave the body, what is the highest dose that can safely be given, and whether it may have an effect on tumors.
Primary Outcome
Adverse events, serious adverse events, ECG monitoring, adrenal function monitoring, monitoring for development of anti-drug antibodies
Interventions
- BIOLOGICAL MGA271
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 179 participants |
| Start Date | 2011-07 |
| Est. Completion | 2019-04-18 |
| Phase | Phase 1 |
What the finished NCT01391143 record still lists
NCT01391143 is an interventional study that assigns participants to a tested intervention. The registered 179 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (198% higher).
The record links to 0 conditions, and to 1 intervention - of which MGA271 is the first listed.
NCT01391143 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01391143 about?
NCT01391143 is a clinical study titled "Safety Study of MGA271 in Refractory Cancer". The purpose of this study is to evaluate the safety of MGA271 when given by intravenous (IV) infusion to patients with refractory cancer. The study will also evaluate how long MGA271 stays in the blood and how long it takes for it to leave the body, what is the highest dose that can safely be given,...
What is the current status of trial NCT01391143?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 179 participants. The study started on 2011-07. Estimated completion is 2019-04-18.
What interventions are being tested in trial NCT01391143?
The interventions under investigation include: MGA271 (BIOLOGICAL).
Who is sponsoring clinical trial NCT01391143?
This trial is sponsored by MacroGenics, which has 36 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01391143's enrollment target sits among peer trials
179 311th of 2000 higher than 1,690 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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