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NCT01379833 · ClinicalTrials.gov registry record
Prevalence of Decreased Corneal Sensation in Patients With Chronic Inflammatory Demyelinating Polyneuropathy
A clinical trial, sponsored by State University of New York at Buffalo.
- Completed
- Registry status
- 18
- Enrollment target
NCT01379833: Completed study, sponsored by State University of New York at Buffalo.
NCT01379833 is a clinical trial that has completed, run by State University of New York at Buffalo. The registered enrollment target is 18 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01379833 has completed, sponsored by State University of New York at Buffalo.
- COMPLETED
- Registry status
- 18 participants
- Enrollment target
Study Summary
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a demyelinating chronic progressive or relapsing neuropathy believed to be secondary to an autoimmune response against peripheral nerve antigens.5 We have observed two patients with CIDP with decreased corneal sensation who also suffered neurotrophic corneal ulcers and severe visual loss in the affected eyes. We want to explore the relationship of CIDP and corneal sensitivity. Our hypothesis is that people with CIDP have decreased corneal sensation compared to those without. We plan to perform a prospective study measuring corneal sensation in patients (proposed n=10) with CIDP and without to determine (1) if a difference exists in patients with CIDP compared to controls and (2) the magnitude of the difference. If a difference is detected in corneal sensitivity in patients with CIDP, this awareness amongst physicians and patients may help prevent blinding complications.
Primary Outcome
The most important variable here is corneal sensitivity in study subjects vs. controls. This is a prospective screen to determine if a difference exists before pursuing larger studies. The endpoint for this investigation will be analysis of 10 patients with CIDP and 10 age-matched controls.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2011-05 |
| Est. Completion | 2013-12 |
What the finished NCT01379833 record still lists
NCT01379833 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 18 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01379833 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01379833 about?
NCT01379833 is a clinical study titled "Prevalence of Decreased Corneal Sensation in Patients With Chronic Inflammatory Demyelinating Polyneuropathy". Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a demyelinating chronic progressive or relapsing neuropathy believed to be secondary to an autoimmune response against peripheral nerve antigens.5 We have observed two patients with CIDP with decreased corneal sensation who also suf...
What is the current status of trial NCT01379833?
This trial is currently completed. The enrollment target is 18 participants. The study started on 2011-05. Estimated completion is 2013-12.
Who is sponsoring clinical trial NCT01379833?
This trial is sponsored by State University of New York at Buffalo, which has 243 total clinical trials registered on ClinicalTrials.gov.
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