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NCT01363141 · ClinicalTrials.gov registry record · NA

Effect of a Low Advanced Glycation End Products (AGE) Diet in the Metabolic Syndrome

A NA study, sponsored by Icahn School of Medicine at Mount Sinai.

Completed
Registry status
NA
Development phase
383
Enrollment target

NCT01363141: Completed NA study, sponsored by Icahn School of Medicine at Mount Sinai.

NCT01363141 is a NA study that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 383 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01363141, a NA study, has completed, sponsored by Icahn School of Medicine at Mount Sinai.

COMPLETED
Registry status
NA
Development phase
383 participants
Enrollment target

Study Summary

The investigators have previously demonstrated that Advanced Glycation End products (AGEs) are associated with several chronic diseases in humans and that blood AGE levels can be significantly reduced by simply changing the way food is cooked. This is an interventional-randomized study in which we are trying to determine whether a diet low in AGE followed for 1 year can effectively reduce circulating AGE levels as well as markers of the metabolic syndrome in a group of patients with these abnormal markers.

Primary Outcome

To test whether prolonged (1 year) dietary AGE restriction, while maintaining caloric intake, can improve insulin resistance in subjects with metabolic syndrome. Insulin resistance will be assessed by measuring simultaneously blood glucose and insulin levels in the fasting state and during an oral glucose tolerance test.

Interventions

  • OTHER Regular AGE Diet
  • OTHER Low AGE Diet

Trial Details

FieldValue
Enrollment Target 383 participants
Start Date 2010-12
Est. Completion 2014-12
Phase NA

What the finished NCT01363141 record still lists

NCT01363141 is an interventional study that assigns participants to a tested intervention. The registered 383 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (73% lower).

The record links to 0 conditions, and to 2 interventions - of which Regular AGE Diet is the first listed.

NCT01363141 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01363141 about?

NCT01363141 is a clinical study titled "Effect of a Low Advanced Glycation End Products (AGE) Diet in the Metabolic Syndrome". The investigators have previously demonstrated that Advanced Glycation End products (AGEs) are associated with several chronic diseases in humans and that blood AGE levels can be significantly reduced by simply changing the way food is cooked. This is an interventional-randomized study in which we ...

What is the current status of trial NCT01363141?

This trial is currently completed. It is a NA study. The enrollment target is 383 participants. The study started on 2010-12. Estimated completion is 2014-12.

What interventions are being tested in trial NCT01363141?

The interventions under investigation include: Regular AGE Diet (OTHER), Low AGE Diet (OTHER).

Who is sponsoring clinical trial NCT01363141?

This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01363141's enrollment target sits among peer trials

383 273rd of 2000 higher than 1,728 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01363141, the US trial registry maintained by the National Library of Medicine. NCT01363141 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.