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NCT01357395 · ClinicalTrials.gov registry record · Phase 2

A Phase 2, Open-Label Study of Amuvatinib in Combination With Platinum-Etoposide Chemotherapy in Small Cell Lung Cancer

A Phase 2 study, sponsored by Astex Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
23
Enrollment target

NCT01357395: Completed Phase 2 study, sponsored by Astex Pharmaceuticals.

NCT01357395 is a Phase 2 study that has completed, run by Astex Pharmaceuticals. The registered enrollment target is 23 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01357395, a Phase 2 study, has completed, sponsored by Astex Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
23 participants
Enrollment target

Study Summary

The purpose of the study is to evaluate the safety and potential benefit of combination amuvatinib with standard of care chemotherapy treatment (platinum and etoposide) in small cell lung cancer (SCLC) subjects.

Interventions

  • DRUG Amuvatinib

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2011-05
Est. Completion 2012-05-28
Phase Phase 2
Astex Pharmaceuticals

38 total trials

What the finished NCT01357395 record still lists

NCT01357395 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 1 intervention - of which Amuvatinib is the first listed.

NCT01357395 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01357395 about?

NCT01357395 is a clinical study titled "A Phase 2, Open-Label Study of Amuvatinib in Combination With Platinum-Etoposide Chemotherapy in Small Cell Lung Cancer". The purpose of the study is to evaluate the safety and potential benefit of combination amuvatinib with standard of care chemotherapy treatment (platinum and etoposide) in small cell lung cancer (SCLC) subjects.

What is the current status of trial NCT01357395?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2011-05. Estimated completion is 2012-05-28.

What interventions are being tested in trial NCT01357395?

The interventions under investigation include: Amuvatinib (DRUG).

Who is sponsoring clinical trial NCT01357395?

This trial is sponsored by Astex Pharmaceuticals, which has 38 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01357395's enrollment target sits among peer trials

23 1784th of 2000 higher than 211 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01357395, the US trial registry maintained by the National Library of Medicine. NCT01357395 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.