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NCT01350401 · ClinicalTrials.gov registry record · Phase 1
Phase I/II Study to Assess the Safety and Activity of Enhanced TCR Transduced Autologous T Cells in Metastatic Melanoma
A Phase 1 study, sponsored by Adaptimmune.
- Terminated
- Registry status
- Phase 1
- Development phase
- 4
- Enrollment target
NCT01350401: Clinical Trial Phase 1 study, sponsored by Adaptimmune.
NCT01350401 is a Phase 1 study that was terminated before completion, run by Adaptimmune. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01350401, a Phase 1 study, was terminated before completion, sponsored by Adaptimmune.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 4 participants
- Enrollment target
Study Summary
The purpose of this early (phase I/II) clinical trial is to assess the effects (both good and bad) of genetically modified T cells after chemotherapy on your cancer and general health.
Primary Outcome
Number of Participants with NCI CTC V.4 Adverse Events related to study treatment greater than or equal to Grade 3
Interventions
- GENETIC Autologous genetically modified T cells, NY-ESO-1ᶜ²⁵⁹T
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2011-06-01 |
| Est. Completion | 2018-03-01 |
| Phase | Phase 1 |
Why NCT01350401 stopped before completion
NCT01350401 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which Autologous genetically modified T cells, NY-ESO-1ᶜ²⁵⁹T is the first listed.
NCT01350401 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01350401 about?
NCT01350401 is a clinical study titled "Phase I/II Study to Assess the Safety and Activity of Enhanced TCR Transduced Autologous T Cells in Metastatic Melanoma". The purpose of this early (phase I/II) clinical trial is to assess the effects (both good and bad) of genetically modified T cells after chemotherapy on your cancer and general health.
What is the current status of trial NCT01350401?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2011-06-01. Estimated completion is 2018-03-01.
What interventions are being tested in trial NCT01350401?
The interventions under investigation include: Autologous genetically modified T cells, NY-ESO-1ᶜ²⁵⁹T (GENETIC).
Who is sponsoring clinical trial NCT01350401?
This trial is sponsored by Adaptimmune, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01350401's enrollment target sits among peer trials
4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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