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NCT01342926 · ClinicalTrials.gov registry record · Phase 2

Clinical Study to Investigate Safety and Efficacy of GSK933776 in Adult Patients With Geographic Atrophy Secondary to Age-related Macular Degeneration

A Phase 2 study, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 2
Development phase
191
Enrollment target

NCT01342926: Completed Phase 2 study, sponsored by GlaxoSmithKline.

NCT01342926 is a Phase 2 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 191 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01342926, a Phase 2 study, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 2
Development phase
191 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety and efficacy of GSK933776 in the treatment of geographic atrophy secondary to age-related macular degeneration.

Primary Outcome

Atrophic age-related macular degeneration (AMD) also called GA is characterized by thinning of the retinal pigment epithelium (RPE) and underlying choriocapillaris, as well as overlying photoreceptors in the macula. GA was evaluated by color FP at the indicated time points: screening, 6 months, 12 months and 18 months. Change from BL: (screening, month 6, 12 or 18 value minus BL value. Note screening occurs prior to BL). Only participants available at the specified time points were analyzed (rep

Interventions

  • DRUG Placebo
  • DRUG GSK933776

Trial Details

FieldValue
Enrollment Target 191 participants
Start Date 2011-06-01
Est. Completion 2016-04-01
Phase Phase 2
GlaxoSmithKline

1,345 total trials

What the finished NCT01342926 record still lists

NCT01342926 is an interventional study that assigns participants to a tested intervention. The registered 191 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01342926 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01342926 about?

NCT01342926 is a clinical study titled "Clinical Study to Investigate Safety and Efficacy of GSK933776 in Adult Patients With Geographic Atrophy Secondary to Age-related Macular Degeneration". The purpose of this study is to determine the safety and efficacy of GSK933776 in the treatment of geographic atrophy secondary to age-related macular degeneration.

What is the current status of trial NCT01342926?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 191 participants. The study started on 2011-06-01. Estimated completion is 2016-04-01.

What interventions are being tested in trial NCT01342926?

The interventions under investigation include: Placebo (DRUG), GSK933776 (DRUG).

Who is sponsoring clinical trial NCT01342926?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01342926's enrollment target sits among peer trials

191 353rd of 2000 higher than 1,648 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01342926, the US trial registry maintained by the National Library of Medicine. NCT01342926 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.