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NCT01342029 · ClinicalTrials.gov registry record · NA

Treatment With Ranolazine in Microvascular Coronary Dysfunction (MCD): Impact on Angina Myocardial Ischemia

A NA study, sponsored by Cedars-Sinai Medical Center.

Completed
Registry status
NA
Development phase
142
Enrollment target

NCT01342029: Completed NA study, sponsored by Cedars-Sinai Medical Center.

NCT01342029 is a NA study that has completed, run by Cedars-Sinai Medical Center. The registered enrollment target is 142 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01342029, a NA study, has completed, sponsored by Cedars-Sinai Medical Center.

COMPLETED
Registry status
NA
Development phase
142 participants
Enrollment target

Study Summary

This research study is designed to test the use of ranolazine in patients with angina (chest discomfort due to reduced blood supply to the heart) due to microvascular coronary dysfunction (MCD; abnormalities in the small blood vessels of the heart). This drug is approved by the U.S. Food and Drug Administration (FDA) for treatment of chronic angina. The FDA has approved this drug based on studies primarily on patients with chronic angina with major blockages of the arteries.

Primary Outcome

Questionnaires will be completed (SAQ - Seattle Angina Questionnaire) at the end of each treatment period. The Seattle Angina Questionnaire (SAQ) is a self-administered, 19-item questionnaire, a cardiac disease-related quality-of-life measure. The SAQ is well validated and sensitive to clinical changes. It has five subscales: physical limitation, angina stability, angina frequency, treatment satisfaction, and quality of life. The possible range of scores for each of the five subscales is 0 to 1

Interventions

  • DRUG Placebo
  • DRUG Ranolazine

Trial Details

FieldValue
Enrollment Target 142 participants
Start Date 2011-05
Est. Completion 2016-12
Phase NA
Cedars-Sinai Medical Center

339 total trials

What the finished NCT01342029 record still lists

NCT01342029 is an interventional study that assigns participants to a tested intervention. The registered 142 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01342029 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01342029 about?

NCT01342029 is a clinical study titled "Treatment With Ranolazine in Microvascular Coronary Dysfunction (MCD): Impact on Angina Myocardial Ischemia". This research study is designed to test the use of ranolazine in patients with angina (chest discomfort due to reduced blood supply to the heart) due to microvascular coronary dysfunction (MCD; abnormalities in the small blood vessels of the heart). This drug is approved by the U.S. Food and Drug Ad...

What is the current status of trial NCT01342029?

This trial is currently completed. It is a NA study. The enrollment target is 142 participants. The study started on 2011-05. Estimated completion is 2016-12.

What interventions are being tested in trial NCT01342029?

The interventions under investigation include: Placebo (DRUG), Ranolazine (DRUG).

Who is sponsoring clinical trial NCT01342029?

This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01342029's enrollment target sits among peer trials

142 711th of 2000 higher than 1,289 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01342029, the US trial registry maintained by the National Library of Medicine. NCT01342029 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.