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NCT01339897 · ClinicalTrials.gov registry record · Phase 1

A Safety Study Evaluating N6022 in Multiple-Ascending Doses in Healthy Subjects

A Phase 1 study, sponsored by Nivalis Therapeutics.

Completed
Registry status
Phase 1
Development phase
25
Enrollment target

NCT01339897: Completed Phase 1 study, sponsored by Nivalis Therapeutics.

NCT01339897 is a Phase 1 study that has completed, run by Nivalis Therapeutics. The registered enrollment target is 25 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01339897, a Phase 1 study, has completed, sponsored by Nivalis Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
25 participants
Enrollment target

Study Summary

This Phase 1 study will evaluate multiple doses across a range that has been found to be effective in mouse models of asthma and safe in one Phase 1 clinical trial. It is intended to provide evidence of the tolerability of multiple doses as well as provide information on the Pharmacokinetic (PK) and metabolism of N6022 in humans.

Primary Outcome

Safety variables (adverse events, vital signs, physical examination, telemetry, 12-lead ECG, infusion site reactions, O2 saturation, and clinical laboratory assessments)

Interventions

  • DRUG Placebo
  • DRUG 5 mg/N6022
  • DRUG 10mg/N6022
  • DRUG 20mg/N6022

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2011-04
Est. Completion 2011-08
Phase Phase 1
Nivalis Therapeutics

10 total trials

What the finished NCT01339897 record still lists

NCT01339897 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower).

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT01339897 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01339897 about?

NCT01339897 is a clinical study titled "A Safety Study Evaluating N6022 in Multiple-Ascending Doses in Healthy Subjects". This Phase 1 study will evaluate multiple doses across a range that has been found to be effective in mouse models of asthma and safe in one Phase 1 clinical trial. It is intended to provide evidence of the tolerability of multiple doses as well as provide information on the Pharmacokinetic (PK) and...

What is the current status of trial NCT01339897?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2011-04. Estimated completion is 2011-08.

What interventions are being tested in trial NCT01339897?

The interventions under investigation include: Placebo (DRUG), 5 mg/N6022 (DRUG), 10mg/N6022 (DRUG), 20mg/N6022 (DRUG).

Who is sponsoring clinical trial NCT01339897?

This trial is sponsored by Nivalis Therapeutics, which has 10 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01339897's enrollment target sits among peer trials

25 1495th of 2000 higher than 481 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01339897, the US trial registry maintained by the National Library of Medicine. NCT01339897 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.