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NCT01337986 · ClinicalTrials.gov registry record · Phase 2

Ampyra for Optic Neuritis in Multiple Sclerosis

A Phase 2 study, sponsored by Washington University School of Medicine.

Completed
Registry status
Phase 2
Development phase
53
Enrollment target

NCT01337986 is a Phase 2 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 53 participants.

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The verdict

NCT01337986, a Phase 2 study, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
Phase 2
Development phase
53 participants
Enrollment target

Study Summary

Fifty subjects will be enrolled in this Phase II, investigator-initiated, randomized and blinded cross-over trial of dalfampridine of 8 weeks duration The study will test the hypothesis that dalfampridine, when administered to subjects with incomplete visual recovery after optic neuritis from MS, will result in symptomatic improvement in visual function. The study will consist of one screening/baseline visit, one visit during treatment with active drug, and one visit on placebo. After the baseline visit, subjects will be randomly assigned to receive study medication or placebo for the first three weeks, followed by a two week wash-out, and then treatment reallocation for the latter three weeks.

Interventions

  • DRUG Dalfampridine/Placebo
  • DRUG Placebo/Dalfampridine

Trial Details

FieldValue
Enrollment Target 53 participants
Start Date 2011-05
Est. Completion 2013-12
Phase Phase 2

What the Registry Record Tells You About NCT01337986

The ClinicalTrials.gov registry entry for NCT01337986 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Dalfampridine/Placebo is the first listed.

NCT01337986 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01337986 about?

NCT01337986 is a clinical study titled "Ampyra for Optic Neuritis in Multiple Sclerosis". Fifty subjects will be enrolled in this Phase II, investigator-initiated, randomized and blinded cross-over trial of dalfampridine of 8 weeks duration The study will test the hypothesis that dalfampridine, when administered to subjects with incomplete visual recovery after optic neuritis from MS, wi...

What is the current status of trial NCT01337986?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 53 participants. The study started on 2011-05. Estimated completion is 2013-12.

What interventions are being tested in trial NCT01337986?

The interventions under investigation include: Dalfampridine/Placebo (DRUG), Placebo/Dalfampridine (DRUG).

Who is sponsoring clinical trial NCT01337986?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.