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NCT01333956 · ClinicalTrials.gov registry record · Phase 1
Effects of Pregabalin on Pain After Total Knee Arthroplasty
A Phase 1 study of Primary Total Knee Arthroplasty, sponsored by Hospital for Special Surgery, New York.
- Completed
- Registry status
- Phase 1
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT01333956 is a Phase 1 study of Primary Total Knee Arthroplasty that has completed, run by Hospital for Special Surgery, New York. The registered enrollment target is 120 participants. The trial reports 1 study location across 1 state.
The verdict
NCT01333956, a Phase 1 study of Primary Total Knee Arthroplasty, has completed, sponsored by Hospital for Special Surgery, New York.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
Total knee arthroplasty can cause severe postoperative pain, and patients typically receive oral opioid analgesics for over 2 weeks. Side effects of pain management may impair participation in physical therapy and diminish patient satisfaction. Anecdotally, it seems that pregabalin is very helpful to patients after total knee arthroplasty. However, pregabalin can have side effects. It is not clear how much pregabalin to prescribe. Low doses may not be effective, but use of high doses may increase the incidence and severity of side effects.The purpose of this study is to determine which dosage of pregabalin is the most effective at reducing pain after knee surgery.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Pregabalin 100mg
- DRUG Pregabalin 50mg
- DRUG Pregabalin 150mg
Study Locations (1)
New York
- Hospital for Special Surgery - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2011-05 |
| Est. Completion | 2013-06 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01333956
The ClinicalTrials.gov registry entry for NCT01333956 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hospital for Special Surgery, New York, which has 194 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Primary Total Knee Arthroplasty appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.
NCT01333956 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT01333956 about?
NCT01333956 is a clinical study titled "Effects of Pregabalin on Pain After Total Knee Arthroplasty". Total knee arthroplasty can cause severe postoperative pain, and patients typically receive oral opioid analgesics for over 2 weeks. Side effects of pain management may impair participation in physical therapy and diminish patient satisfaction. Anecdotally, it seems that pregabalin is very helpful t...
What is the current status of trial NCT01333956?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 120 participants. The study started on 2011-05. Estimated completion is 2013-06.
What conditions does trial NCT01333956 study?
This clinical trial studies the following conditions: Primary Total Knee Arthroplasty.
What interventions are being tested in trial NCT01333956?
The interventions under investigation include: Placebo (DRUG), Pregabalin 100mg (DRUG), Pregabalin 50mg (DRUG), Pregabalin 150mg (DRUG).
Who is sponsoring clinical trial NCT01333956?
This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01333956 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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