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NCT01326481 · ClinicalTrials.gov registry record · Phase 1

Open Label Dose-Finding Study of TRC105 Plus Capecitabine for Metastatic Breast Cancer

A Phase 1 study of Metastatic Breast Cancer, sponsored by Tracon Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
19
Enrollment target
2
Study locations

NCT01326481 is a Phase 1 study of Metastatic Breast Cancer that has completed, run by Tracon Pharmaceuticals. The registered enrollment target is 19 participants, below the 205-participant average among 139 other Metastatic Breast Cancer trials with a reported enrollment target (91% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT01326481, a Phase 1 study of Metastatic Breast Cancer, has completed, sponsored by Tracon Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
19 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to determine the recommended phase 2 dose and overall safety and tolerability of TRC105 when given in combination with capecitabine for the treatment of patients with progressive or recurrent metastatic breast cancer.

Conditions Studied

Interventions

  • DRUG Capecitabine
  • DRUG TRC105

Study Locations (2)

Alabama

  • University of Alabama at Birmingham - Birmingham

New York

  • Roswell Park Cancer Institute - Buffalo

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2011-06
Est. Completion 2014-12
Phase Phase 1

Sponsor

Tracon Pharmaceuticals

16 total trials

What the Registry Record Tells You About NCT01326481

The ClinicalTrials.gov registry entry for NCT01326481 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 205-participant average among 139 other Metastatic Breast Cancer trials with a reported enrollment target (91% lower). The listed sponsor is Tracon Pharmaceuticals, which has 16 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Metastatic Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Capecitabine is the first listed.

NCT01326481 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Alabama, New York.

Frequently Asked Questions

What is clinical trial NCT01326481 about?

NCT01326481 is a clinical study titled "Open Label Dose-Finding Study of TRC105 Plus Capecitabine for Metastatic Breast Cancer". The purpose of this study is to determine the recommended phase 2 dose and overall safety and tolerability of TRC105 when given in combination with capecitabine for the treatment of patients with progressive or recurrent metastatic breast cancer.

What is the current status of trial NCT01326481?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2011-06. Estimated completion is 2014-12.

What conditions does trial NCT01326481 study?

This clinical trial studies the following conditions: Metastatic Breast Cancer.

What interventions are being tested in trial NCT01326481?

The interventions under investigation include: Capecitabine (DRUG), TRC105 (DRUG).

Who is sponsoring clinical trial NCT01326481?

This trial is sponsored by Tracon Pharmaceuticals, which has 16 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01326481 being conducted?

This trial has 2 study locations across Alabama, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.