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NCT01325610 · ClinicalTrials.gov registry record · NA
Vitamin D Effect on Calcium Absorption on Persons on Hemodialysis
A NA study, sponsored by Creighton University.
- Completed
- Registry status
- NA
- Development phase
- 37
- Enrollment target
NCT01325610 is a NA study that has completed, run by Creighton University. The registered enrollment target is 37 participants.
The verdict
NCT01325610, a NA study, has completed, sponsored by Creighton University.
- COMPLETED
- Registry status
- NA
- Development phase
- 37 participants
- Enrollment target
Study Summary
The assumption has been that 1,25(OH)2D is solely responsible for calcium absorption. That has been one of the presumed causes of hyperparathyroidism in chronic kidney disease (CKD) (low 1,25(OH)2D leads to decreased calcium absorption, which increases parathyroid hormone release in compensation). Replacing 1,25 D directly has been the goal with using 1,25D or its analogues in CKD. There is very little data concerning use of native vitamin D or 25(OH)D in CKD, although autocrine functions in extrarenal tissues would use 25(OH)D. The latest KDIGO guidelines do recognize the autocrine role of vitamin D, but have no data on outcomes or doses or optimal levels to guide them and so have made a blanket recommendation to treat 25D levels in CKD by general healthy population guidelines. 1. This project focuses on an outcome (calcium absorption) that may be impacted by optimizing 25D status in renal patients. The investigators will assume for this project that a level of 25D \> 32 ng/ml is optimal in CKD patients as in a healthy population. 2. A secondary outcome is to quantify calcium absorption in CKD patients with and without vitamin D repletion and to quantify systemic 1,25D levels. This may clarify the roles 25D and 1,25D play in calcium absorption.
Interventions
- DIETARY_SUPPLEMENT cholecalciferol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2011-04 |
| Est. Completion | 2012-02 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01325610
The ClinicalTrials.gov registry entry for NCT01325610 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Creighton University, which has 98 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which cholecalciferol is the first listed.
NCT01325610 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01325610 about?
NCT01325610 is a clinical study titled "Vitamin D Effect on Calcium Absorption on Persons on Hemodialysis". The assumption has been that 1,25(OH)2D is solely responsible for calcium absorption. That has been one of the presumed causes of hyperparathyroidism in chronic kidney disease (CKD) (low 1,25(OH)2D leads to decreased calcium absorption, which increases parathyroid hormone release in compensation). R...
What is the current status of trial NCT01325610?
This trial is currently completed. It is a NA study. The enrollment target is 37 participants. The study started on 2011-04. Estimated completion is 2012-02.
What interventions are being tested in trial NCT01325610?
The interventions under investigation include: cholecalciferol (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01325610?
This trial is sponsored by Creighton University, which has 98 total clinical trials registered on ClinicalTrials.gov.
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