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NCT01324453 · ClinicalTrials.gov registry record · Phase 1
Phase II Clinical Trial to Evaluate the Benefits of Postconditioning in ST-Elevation Myocardial Infarction (STEMI)
A Phase 1 study, sponsored by Minneapolis Heart Institute Foundation.
- Completed
- Registry status
- Phase 1
- Development phase
- 103
- Enrollment target
NCT01324453: Completed Phase 1 study, sponsored by Minneapolis Heart Institute Foundation.
NCT01324453 is a Phase 1 study that has completed, run by Minneapolis Heart Institute Foundation. The registered enrollment target is 103 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01324453, a Phase 1 study, has completed, sponsored by Minneapolis Heart Institute Foundation.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 103 participants
- Enrollment target
Study Summary
This study will evaluate change in heart muscle function from baseline to three months and twelve months in participants who present with a heart attack and a completely occluded coronary artery. These subjects will be randomized to receive standard Percutaneous transluminal coronary angioplasty (PTCA)/Stenting to open the artery or routine PTCA/Stenting plus post conditioning. Post conditioning commences immediately upon reperfusion using four cycles of thirty second inflations with a standard angioplasty balloon followed by a thirty seconds of reperfusion. The investigators hypothesize that Postconditioning reduces the size of the heart attack when utilized with successful primary Angioplasty/stent.
Primary Outcome
Infarct size was quantified by delayed, contrast-enhanced MRI
Interventions
- PROCEDURE Post Conditioning + Primary PCI
- PROCEDURE Standard Primary PCI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 103 participants |
| Start Date | 2011-03 |
| Est. Completion | 2017-03 |
| Phase | Phase 1 |
What the finished NCT01324453 record still lists
NCT01324453 is an interventional study that assigns participants to a tested intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% higher).
The record links to 0 conditions, and to 2 interventions - of which Post Conditioning + Primary PCI is the first listed.
NCT01324453 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01324453 about?
NCT01324453 is a clinical study titled "Phase II Clinical Trial to Evaluate the Benefits of Postconditioning in ST-Elevation Myocardial Infarction (STEMI)". This study will evaluate change in heart muscle function from baseline to three months and twelve months in participants who present with a heart attack and a completely occluded coronary artery. These subjects will be randomized to receive standard Percutaneous transluminal coronary angioplasty (PT...
What is the current status of trial NCT01324453?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 103 participants. The study started on 2011-03. Estimated completion is 2017-03.
What interventions are being tested in trial NCT01324453?
The interventions under investigation include: Post Conditioning + Primary PCI (PROCEDURE), Standard Primary PCI (PROCEDURE).
Who is sponsoring clinical trial NCT01324453?
This trial is sponsored by Minneapolis Heart Institute Foundation, which has 22 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01324453's enrollment target sits among peer trials
103 541st of 2000 higher than 1,458 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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