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NCT01318811 · ClinicalTrials.gov registry record · Phase 4
A Comparison of Dilute Versus Concentrated Heparin for CRRT Anticoagulation
A Phase 4 study, sponsored by Vanderbilt University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 12
- Enrollment target
NCT01318811 is a Phase 4 study that was terminated before completion, run by Vanderbilt University. The registered enrollment target is 12 participants.
The verdict
NCT01318811, a Phase 4 study, was terminated before completion, sponsored by Vanderbilt University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 12 participants
- Enrollment target
Study Summary
Heparin is commonly used for anticoagulation of the extracorporeal circuit during continuous renal replacement therapy (CRRT) but the optimal mode of delivery has not yet been validated. Our study will compare dilute heparin to a standard concentration of heparin. The investigators hypothesize that heparin delivered in a dilute solution will augment coating of the filter fibers with anticoagulants, decreasing clotting events and increasing filter life. By improving delivery of heparin to the filter and circuit, where clotting events can disrupt dialysis, less heparin would be required for the extra-corporeal circuit and thus less heparin would be delivered back to the patient with blood return from the machine. By exposing the patient to less heparin it is hypothesized that fewer bleeding events would occur, making the dialysis treatment safer. If more of the filter's fibers remain patent and the filter is functional for a longer period of time, the CRRT would also be more effective.
Interventions
- DRUG Dilute unfractionated heparin
- DRUG Standard concentration unfractionated heparin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2011-03 |
| Est. Completion | 2016-04-03 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01318811
The ClinicalTrials.gov registry entry for NCT01318811 describes a study currently listed as terminated, categorized as Phase 4. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Dilute unfractionated heparin is the first listed.
NCT01318811 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01318811 about?
NCT01318811 is a clinical study titled "A Comparison of Dilute Versus Concentrated Heparin for CRRT Anticoagulation". Heparin is commonly used for anticoagulation of the extracorporeal circuit during continuous renal replacement therapy (CRRT) but the optimal mode of delivery has not yet been validated. Our study will compare dilute heparin to a standard concentration of heparin. The investigators hypothesize that ...
What is the current status of trial NCT01318811?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 12 participants. The study started on 2011-03. Estimated completion is 2016-04-03.
What interventions are being tested in trial NCT01318811?
The interventions under investigation include: Dilute unfractionated heparin (DRUG), Standard concentration unfractionated heparin (DRUG).
Who is sponsoring clinical trial NCT01318811?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
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