Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01318304 · ClinicalTrials.gov registry record
Vaginal Innate Immunity in Normal and HIV-Infected Women
A clinical trial, sponsored by Boston Medical Center.
- Completed
- Registry status
- 83
- Enrollment target
NCT01318304 is a clinical trial that has completed, run by Boston Medical Center. The registered enrollment target is 83 participants.
The verdict
NCT01318304 has completed, sponsored by Boston Medical Center.
- COMPLETED
- Registry status
- 83 participants
- Enrollment target
Study Summary
The innate immunity of the vaginal tract provides first-line defense from abnormal microorganisms or overgrowth of common organisms, such as Candida species or Gardnerella vaginalis. It is unclear from the current available literature whether the rate of vaginal infection increases or decreases in frequency during pregnancy when compared to the non-pregnant state, but this may be predicted by shifts in vaginal innate immunity. Vaginal infections are important players in HIV disease, potentially increasing the risk of viral transmission. In addition, these infections may activate inflammatory markers in the reproductive tract and increase the risk of premature delivery or other negative pregnancy outcomes. The vaginal innate immune system has not been well characterized in pregnant women, or in women with HIV infection. The study of how this system changes in pregnancy and HIV infection will provide essential knowledge for further study of vaginal mucosal protection. The investigators study is an observational study designed to compare levels of vaginal innate immunity markers in women based on a) pregnancy status and b) HIV infection status. Comparisons will be made between pregnant and non- pregnant women and between HIV positive and HIV negative women. The investigators hypothesize that there will be significant differences in levels of innate immunity between the groups.
Interventions
- OTHER Vaginal lavage specimen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 83 participants |
| Start Date | 2010-10 |
| Est. Completion | 2013-04 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01318304
The ClinicalTrials.gov registry entry for NCT01318304 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 83 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boston Medical Center, which has 253 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Vaginal lavage specimen is the first listed.
NCT01318304 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01318304 about?
NCT01318304 is a clinical study titled "Vaginal Innate Immunity in Normal and HIV-Infected Women". The innate immunity of the vaginal tract provides first-line defense from abnormal microorganisms or overgrowth of common organisms, such as Candida species or Gardnerella vaginalis. It is unclear from the current available literature whether the rate of vaginal infection increases or decreases in f...
What is the current status of trial NCT01318304?
This trial is currently completed. The enrollment target is 83 participants. The study started on 2010-10. Estimated completion is 2013-04.
What interventions are being tested in trial NCT01318304?
The interventions under investigation include: Vaginal lavage specimen (OTHER).
Who is sponsoring clinical trial NCT01318304?
This trial is sponsored by Boston Medical Center, which has 253 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.