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NCT01317927 · ClinicalTrials.gov registry record · Phase 1
A Study of Belinostat in Combination With Warfarin in Patients With Solid Tumors or Hematological Malignancies
A Phase 1 study, sponsored by Spectrum Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 27
- Enrollment target
NCT01317927: Completed Phase 1 study, sponsored by Spectrum Pharmaceuticals.
NCT01317927 is a Phase 1 study that has completed, run by Spectrum Pharmaceuticals. The registered enrollment target is 27 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01317927, a Phase 1 study, has completed, sponsored by Spectrum Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 27 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the plasma concentration and pharmacodynamics effects of warfarin 5 mg, in the presence or absence of belinostat 1,000 mg/m². Pharmacokinetic evaluation of belinostat 1,000 mg/m² and metabolites in the presence of warfarin 5 mg.
Primary Outcome
Samples will be analyzed for S-warfarin and R-warfarin analytes in all evaluable subjects at the end of the trial
Interventions
- DRUG Belinostat, Warfarin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2010-12 |
| Est. Completion | 2015-06 |
| Phase | Phase 1 |
What the finished NCT01317927 record still lists
NCT01317927 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 1 intervention - of which Belinostat, Warfarin is the first listed.
NCT01317927 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01317927 about?
NCT01317927 is a clinical study titled "A Study of Belinostat in Combination With Warfarin in Patients With Solid Tumors or Hematological Malignancies". The purpose of this study is to evaluate the plasma concentration and pharmacodynamics effects of warfarin 5 mg, in the presence or absence of belinostat 1,000 mg/m². Pharmacokinetic evaluation of belinostat 1,000 mg/m² and metabolites in the presence of warfarin 5 mg.
What is the current status of trial NCT01317927?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2010-12. Estimated completion is 2015-06.
What interventions are being tested in trial NCT01317927?
The interventions under investigation include: Belinostat, Warfarin (DRUG).
Who is sponsoring clinical trial NCT01317927?
This trial is sponsored by Spectrum Pharmaceuticals, which has 52 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01317927's enrollment target sits among peer trials
27 1463rd of 2000 higher than 519 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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