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NCT01312857 · ClinicalTrials.gov registry record · Phase 2
Study of Hepatic Arterial Infusion With Intravenous Irinotecan, 5FU and Leucovorin With or Without Panitumumab, in Patients With Wild Type RAS Who Have Resected Hepatic Metastases From Colorectal Cancer
A Phase 2 study of Metastatic Colorectal Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 75
- Enrollment target
- 8
- Study locations
NCT01312857: Completed Phase 2 study of Metastatic Colorectal Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT01312857 is a Phase 2 study of Metastatic Colorectal Cancer that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 75 participants, below the 184-participant average among 45 other Metastatic Colorectal Cancer trials with a reported enrollment target (59% lower). The trial reports 8 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01312857, a Phase 2 study of Metastatic Colorectal Cancer, has completed, sponsored by Memorial Sloan Kettering Cancer Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 75 participants
- Enrollment target
- 8
- Study locations
Study Summary
The purpose of this study is to see if Panitumumab plus the other treatments will increase the time of remission. Remission means that there is no sign of the cancer.
Primary Outcome
to determine if panitumumab with Hepatic Arterial Infusion (HAI) in combination with systemic chemotherapy can increase the recurrence free survival (RFS) for colorectal cancer patients with resected liver metastases
Conditions Studied
Interventions
- DRUG panitumumab
- DRUG Randomization to No Panitumumab
Study Locations (8)
New York
- Memorial Sloan Kettering Commack - Commack
- Memorial Sloan Kettering Westchester - Harrison
- Memorial Sloan Kettering Cancer Center - New York
- Memorial Sloan Kettering Rockville Centre - Rockville Centre
- Memorial Sloan Kettering Nassau - Uniondale
New Jersey
- Memorial Sloan Kettering Basking Ridge - Basking Ridge
- Memorial Sloan Kettering Monmouth - Middletown
- Memorial Sloan Kettering Bergen - Montvale
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2011-03-07 |
| Est. Completion | 2024-07-15 |
| Phase | Phase 2 |
What the finished NCT01312857 record still lists
NCT01312857 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 184-participant average among 45 other Metastatic Colorectal Cancer trials with a reported enrollment target (59% lower).
The record links to 1 condition, with Metastatic Colorectal Cancer appearing as the primary indexed condition, and to 2 interventions - of which panitumumab is the first listed.
NCT01312857 lists 8 locations in 2 states (New York, New Jersey).
Frequently Asked Questions
What is clinical trial NCT01312857 about?
NCT01312857 is a clinical study titled "Study of Hepatic Arterial Infusion With Intravenous Irinotecan, 5FU and Leucovorin With or Without Panitumumab, in Patients With Wild Type RAS Who Have Resected Hepatic Metastases From Colorectal Cancer". The purpose of this study is to see if Panitumumab plus the other treatments will increase the time of remission. Remission means that there is no sign of the cancer.
What is the current status of trial NCT01312857?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 75 participants. The study started on 2011-03-07. Estimated completion is 2024-07-15.
What conditions does trial NCT01312857 study?
This clinical trial studies the following conditions: Metastatic Colorectal Cancer.
What interventions are being tested in trial NCT01312857?
The interventions under investigation include: panitumumab (DRUG), Randomization to No Panitumumab (DRUG).
Who is sponsoring clinical trial NCT01312857?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01312857 being conducted?
This trial has 8 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01312857's enrollment target sits among peer trials
75 27th of 45 higher than 19 of 45 other Metastatic Colorectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metastatic Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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