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NCT01298999 · ClinicalTrials.gov registry record · Phase 2
Trial of a Gastrin Receptor Antagonist in Barrett's Esophagus
A Phase 2 study, sponsored by Columbia University.
- Completed
- Registry status
- Phase 2
- Development phase
- 27
- Enrollment target
NCT01298999: Completed Phase 2 study, sponsored by Columbia University.
NCT01298999 is a Phase 2 study that has completed, run by Columbia University. The registered enrollment target is 27 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01298999, a Phase 2 study, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 27 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether treatment with an experimental drug called YF476 in patients with Barrett's esophagus reduces the expression of tissue markers that are associated with an increased risk of developing esophageal cancer.
Primary Outcome
The study is designed to examine change in tissue Ki67 expression, a marker of cellular proliferation.
Interventions
- DRUG Placebo
- DRUG YF476
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2010-06 |
| Est. Completion | 2017-12 |
| Phase | Phase 2 |
What the finished NCT01298999 record still lists
NCT01298999 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01298999 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01298999 about?
NCT01298999 is a clinical study titled "Trial of a Gastrin Receptor Antagonist in Barrett's Esophagus". The purpose of this study is to determine whether treatment with an experimental drug called YF476 in patients with Barrett's esophagus reduces the expression of tissue markers that are associated with an increased risk of developing esophageal cancer.
What is the current status of trial NCT01298999?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2010-06. Estimated completion is 2017-12.
What interventions are being tested in trial NCT01298999?
The interventions under investigation include: Placebo (DRUG), YF476 (DRUG).
Who is sponsoring clinical trial NCT01298999?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01298999's enrollment target sits among peer trials
27 1697th of 2000 higher than 293 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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