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NCT01297244 · ClinicalTrials.gov registry record · Phase 2
A Biomarker Study of Tivozanib in Subjects With Advanced Renal Cell Carcinoma
A Phase 2 study, sponsored by AVEO Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 105
- Enrollment target
NCT01297244: Completed Phase 2 study, sponsored by AVEO Pharmaceuticals.
NCT01297244 is a Phase 2 study that has completed, run by AVEO Pharmaceuticals. The registered enrollment target is 105 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (21% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01297244, a Phase 2 study, has completed, sponsored by AVEO Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 105 participants
- Enrollment target
Study Summary
This is an open-label, single arm, multicenter study. Subjects will be stratified by histology (clear cell versus non-clear cell). Enrollment of non-clear cell subjects will be limited to ≤ 30% of the entire study population.
Primary Outcome
To Evaluate CD68, HIF (hypoxia induced factor) 1/HIF2, VEGF A, VEGF-B, VEGF-C, VEGF-D, HGF (hepatocyte growth factor), CAIX, and PLGF (placental growth factor) levels and a biomarker signature based on transcriptional profiles.
Interventions
- DRUG Tivozanib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2011-01 |
| Est. Completion | 2012-10 |
| Phase | Phase 2 |
What the finished NCT01297244 record still lists
NCT01297244 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (21% lower).
The record links to 0 conditions, and to 1 intervention - of which Tivozanib is the first listed.
NCT01297244 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01297244 about?
NCT01297244 is a clinical study titled "A Biomarker Study of Tivozanib in Subjects With Advanced Renal Cell Carcinoma". This is an open-label, single arm, multicenter study. Subjects will be stratified by histology (clear cell versus non-clear cell). Enrollment of non-clear cell subjects will be limited to ≤ 30% of the entire study population.
What is the current status of trial NCT01297244?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 105 participants. The study started on 2011-01. Estimated completion is 2012-10.
What interventions are being tested in trial NCT01297244?
The interventions under investigation include: Tivozanib (DRUG).
Who is sponsoring clinical trial NCT01297244?
This trial is sponsored by AVEO Pharmaceuticals, which has 27 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01297244's enrollment target sits among peer trials
105 650th of 2000 higher than 1,341 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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