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NCT01293487 · ClinicalTrials.gov registry record · Phase 1

Safety And Tolerability Study Of RN564 In Women With Osteopenia And Healthy Men.

A Phase 1 study, sponsored by Pfizer.

Completed
Registry status
Phase 1
Development phase
68
Enrollment target

NCT01293487: Completed Phase 1 study, sponsored by Pfizer.

NCT01293487 is a Phase 1 study that has completed, run by Pfizer. The registered enrollment target is 68 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01293487, a Phase 1 study, has completed, sponsored by Pfizer.

COMPLETED
Registry status
Phase 1
Development phase
68 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety and tolerability of RN564 in women with osteopenia and healthy men.

Primary Outcome

Dose-limiting or intolerable treatment related AEs was defined as any of the following criteria occurred in 2 or more participants: Serious adverse events, Increased liver transaminases, Increased bilirubin (in absence of ALT/AST elevations, allergic / hypersensitivity reactions, vasculitis, Musculoskeletal pain, Increased serum creatinine, Diarrhea, enteritis or nausea, Prolongation of QTcF interval or any other criteria If considered appropriate by the Medical Monitor and Investigator. A dose

Interventions

  • BIOLOGICAL RN564

Trial Details

FieldValue
Enrollment Target 68 participants
Start Date 2011-04-01
Est. Completion 2012-05-24
Phase Phase 1
Pfizer

1,845 total trials

What the finished NCT01293487 record still lists

NCT01293487 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% higher).

The record links to 0 conditions, and to 1 intervention - of which RN564 is the first listed.

NCT01293487 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01293487 about?

NCT01293487 is a clinical study titled "Safety And Tolerability Study Of RN564 In Women With Osteopenia And Healthy Men.". The purpose of this study is to determine the safety and tolerability of RN564 in women with osteopenia and healthy men.

What is the current status of trial NCT01293487?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 68 participants. The study started on 2011-04-01. Estimated completion is 2012-05-24.

What interventions are being tested in trial NCT01293487?

The interventions under investigation include: RN564 (BIOLOGICAL).

Who is sponsoring clinical trial NCT01293487?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01293487's enrollment target sits among peer trials

68 776th of 2000 higher than 1,219 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01293487, the US trial registry maintained by the National Library of Medicine. NCT01293487 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.