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NCT01290549 · ClinicalTrials.gov registry record · Phase 1

A Study of Escalating Doses of Polatuzumab Vedotin in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma and Chronic Lymphocytic Leukemia and Polatuzumab Vedotin in Combination With Rituximab in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma

A Phase 1 study, sponsored by Genentech.

Completed
Registry status
Phase 1
Development phase
95
Enrollment target

NCT01290549 is a Phase 1 study that has completed, run by Genentech. The registered enrollment target is 95 participants.

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The verdict

NCT01290549, a Phase 1 study, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 1
Development phase
95 participants
Enrollment target

Study Summary

This is a Phase I, multicenter, open-label, dose-escalation study of polatuzumab vedotin administered as a single agent by intravenous (IV) infusion to participants with relapsed or refractory hematologic malignancies. In Phase Ib, participants will receive polatuzumab vedotin in combination with rituximab.

Interventions

  • DRUG Rituximab
  • DRUG Polatuzumab Vedotin

Trial Details

FieldValue
Enrollment Target 95 participants
Start Date 2011-03-22
Est. Completion 2014-11-18
Phase Phase 1

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT01290549

The ClinicalTrials.gov registry entry for NCT01290549 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 95 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Rituximab is the first listed.

NCT01290549 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01290549 about?

NCT01290549 is a clinical study titled "A Study of Escalating Doses of Polatuzumab Vedotin in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma and Chronic Lymphocytic Leukemia and Polatuzumab Vedotin in Combination With Rituximab in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma". This is a Phase I, multicenter, open-label, dose-escalation study of polatuzumab vedotin administered as a single agent by intravenous (IV) infusion to participants with relapsed or refractory hematologic malignancies. In Phase Ib, participants will receive polatuzumab vedotin in combination with ri...

What is the current status of trial NCT01290549?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 95 participants. The study started on 2011-03-22. Estimated completion is 2014-11-18.

What interventions are being tested in trial NCT01290549?

The interventions under investigation include: Rituximab (DRUG), Polatuzumab Vedotin (DRUG).

Who is sponsoring clinical trial NCT01290549?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.