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NCT01268644 · ClinicalTrials.gov registry record · Phase 1
Effects of Metreleptin in Type 1 Diabetes Mellitus
A Phase 1 study, sponsored by University of Texas Southwestern Medical Center.
- Terminated
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
NCT01268644: Clinical Trial Phase 1 study, sponsored by University of Texas Southwestern Medical Center.
NCT01268644 is a Phase 1 study that was terminated before completion, run by University of Texas Southwestern Medical Center. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01268644, a Phase 1 study, was terminated before completion, sponsored by University of Texas Southwestern Medical Center.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
This study will add leptin therapy to the current insulin therapy of Type 1 Diabetics with the aim of lowering the total insulin requirements and suppressing the steep fluctuations typically associated with Type 1 Diabetes.
Primary Outcome
Change in Hba1c after 12 weeks on Leptin Therapy compared to Baseline value
Interventions
- DRUG Leptin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2010-09 |
| Est. Completion | 2014-08 |
| Phase | Phase 1 |
Why NCT01268644 stopped before completion
NCT01268644 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 1 intervention - of which Leptin is the first listed.
NCT01268644 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01268644 about?
NCT01268644 is a clinical study titled "Effects of Metreleptin in Type 1 Diabetes Mellitus". This study will add leptin therapy to the current insulin therapy of Type 1 Diabetics with the aim of lowering the total insulin requirements and suppressing the steep fluctuations typically associated with Type 1 Diabetes.
What is the current status of trial NCT01268644?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2010-09. Estimated completion is 2014-08.
What interventions are being tested in trial NCT01268644?
The interventions under investigation include: Leptin (DRUG).
Who is sponsoring clinical trial NCT01268644?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01268644's enrollment target sits among peer trials
8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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