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NCT01268111 · ClinicalTrials.gov registry record · Phase 1
Effect of Vitamin D Replacement on Insulin Sensitivity
A Phase 1 study, sponsored by Texas Tech University Health Sciences Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
NCT01268111: Completed Phase 1 study, sponsored by Texas Tech University Health Sciences Center.
NCT01268111 is a Phase 1 study that has completed, run by Texas Tech University Health Sciences Center. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01268111, a Phase 1 study, has completed, sponsored by Texas Tech University Health Sciences Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
Healthy subjects with low Vitamin D levels will be randomly assigned to either Vitamin D replacement or placebo for a period of 8 weeks. Insulin sensitivity will be measured before and after the intervention, and the changes will be compared between the two groups. This will help us understand if Vitamin D replacement improves insulin sensitivity. Serum Retinol Binding Protein 4 levels will also be measured to see if changes in insulin sensitivity are mediated by RBP4.
Primary Outcome
Insulin stimulated glucose uptake will be measured by glucose clamp studies
Interventions
- DRUG Placebo
- DRUG Ergocalciferols
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2011-01 |
| Est. Completion | 2012-03 |
| Phase | Phase 1 |
What the finished NCT01268111 record still lists
NCT01268111 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01268111 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01268111 about?
NCT01268111 is a clinical study titled "Effect of Vitamin D Replacement on Insulin Sensitivity". Healthy subjects with low Vitamin D levels will be randomly assigned to either Vitamin D replacement or placebo for a period of 8 weeks. Insulin sensitivity will be measured before and after the intervention, and the changes will be compared between the two groups. This will help us understand if Vi...
What is the current status of trial NCT01268111?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2011-01. Estimated completion is 2012-03.
What interventions are being tested in trial NCT01268111?
The interventions under investigation include: Placebo (DRUG), Ergocalciferols (DRUG).
Who is sponsoring clinical trial NCT01268111?
This trial is sponsored by Texas Tech University Health Sciences Center, which has 76 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01268111's enrollment target sits among peer trials
12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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