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NCT01262820 · ClinicalTrials.gov registry record · Phase 2

Pazopanib In Stage IIIB/IV NSCLC Lung Cancer After Progression on First Line Therapy Containing Bevacizumab

A Phase 2 study, sponsored by UNC Lineberger Comprehensive Cancer Center.

Completed
Registry status
Phase 2
Development phase
15
Enrollment target

NCT01262820: Completed Phase 2 study, sponsored by UNC Lineberger Comprehensive Cancer Center.

NCT01262820 is a Phase 2 study that has completed, run by UNC Lineberger Comprehensive Cancer Center. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01262820, a Phase 2 study, has completed, sponsored by UNC Lineberger Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
15 participants
Enrollment target

Study Summary

This is an open label Phase II Trial that using the investigational anti-cancer agent, Pazopanib to see whether non-squamous non-small cell lung cancer will respond to its use by decreasing the size of the tumor or stopping its growth.

Primary Outcome

Response (CR + PR + SD) as defined by RECIST v1.1 lasting equal to or greater than 12 weeks in patients treated with pazopanib alone for stage IIIB/IV non-squamous NSCLC after progression on first line therapy containing bevacizumab Per Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.1) : Complete Response (CR) is defined as Disappearance of all target lesions; Partial Response (PR), as a \>=30% decrease in the sum of the diameters (longest for non-nodal lesions, short axis for

Interventions

  • DRUG Pazopanib

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2010-12
Est. Completion 2014-10
Phase Phase 2

What the finished NCT01262820 record still lists

NCT01262820 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).

The record links to 0 conditions, and to 1 intervention - of which Pazopanib is the first listed.

NCT01262820 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01262820 about?

NCT01262820 is a clinical study titled "Pazopanib In Stage IIIB/IV NSCLC Lung Cancer After Progression on First Line Therapy Containing Bevacizumab". This is an open label Phase II Trial that using the investigational anti-cancer agent, Pazopanib to see whether non-squamous non-small cell lung cancer will respond to its use by decreasing the size of the tumor or stopping its growth.

What is the current status of trial NCT01262820?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2010-12. Estimated completion is 2014-10.

What interventions are being tested in trial NCT01262820?

The interventions under investigation include: Pazopanib (DRUG).

Who is sponsoring clinical trial NCT01262820?

This trial is sponsored by UNC Lineberger Comprehensive Cancer Center, which has 366 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01262820's enrollment target sits among peer trials

15 1919th of 2000 higher than 60 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01262820, the US trial registry maintained by the National Library of Medicine. NCT01262820 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.